GEO DataSet Links for SRA (Select 3763234) - GEO DataSets

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Items: 2

Select item 3025161221.

WT3

Organism:: Mus musculus

Source name:: hindlimb muscle

Platform:: GPL17021
Series:: GSE95543

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Sample

Accession:: GSM2516122

ID:: 302516122

SRA Run Selector

Select item 2000955432.

KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination

(Submitter supplied) Maintenance of muscle function requires assembly of contractile proteins into highly organized sarcomeres. Mutations in Kelch-like protein 41 (KLHL41) cause nemaline myopathy, a fatal muscle disorder associated with sarcomere disarray. We generated KLHL41 mutant mice, which display lethal disruption of sarcomeres and aberrant expression of muscle structural and contractile proteins, mimicking the hallmarks of the human disease. more...