GEO DataSet Links for SRA (Select 29430283) - GEO DataSets

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Items: 2

Select item 3077740961.

220718L29_exp220519_MS63_SCGE-04nM-BE_gDNA-seq-rep2

Organism:: Saccharomyces cerevisiae; Nakaseomyces glabratus

Source name:: 220718L29_exp220519_MS63_SCGE-04nM-BE_gDNA-seq-rep2

Platform:: GPL33750
Series:: GSE242874

Download data: BIGWIG

Sample

Accession:: GSM7774096

ID:: 307774096

SRA Run Selector

Select item 2002428742.

RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size

(Submitter supplied) A fundamental feature of cellular growth is that total protein and RNA amounts increase with cell size to keep concentrations approximately constant. A key component to this is that global transcription rates increase in larger cells. Here, we identify RNAPII as the limiting factor scaling mRNA transcription with cell size in budding yeast, as transcription is highly sensitive to the dosage of RNAPII but not to other components of the transcriptional machinery. more...