GEO DataSet Links for SRA (Select 28879370) - GEO DataSets

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Items: 2

Select item 3077210601.

wt_r1_t06_input

Organism:: Escherichia coli str. K-12 substr. MG1655

Source name:: cells

Platform:: GPL33080
Series:: GSE241319 GSE241322

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Accession:: GSM7721060

ID:: 307721060

SRA Run Selector

Select item 2002413192.

Bacterial Stress Bodies – Ancestral Condensates Regulating RNA Turnover and Protein Translation II

(Submitter supplied) How biomolecules condense to organize subcellular processes is of fundamental significance. Nitrogen-starved Escherichia coli form a single condensate, which we termed Bacterial Stress Body (BSB). Its formation is triggered by long polyphosphate chains, which scaffold the RNA chaperone Hfq into high molecular weight complexes with distinct sequence-specific RNA and DNA binding properties. We show that polyP is crucial for the stabilization of select RNAs, the sequestration of translation- and RNA metabolism-associated proteins that likely stall protein synthesis, and the specific nucleoid-associated localization of BSBs. more...