GEO DataSet Links for SRA (Select 2311792) - GEO DataSets

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Links from SRA

Items: 2

Select item 3020831361.

NPC2 whole chromatin rep2 64U MNase

Organism:: Mus musculus

Source name:: Embryonic neural progenitors

Platform:: GPL17021
Series:: GSE78984

Download data: BEDGRAPH

Sample

Accession:: GSM2083136

ID:: 302083136

SRA Run Selector

Select item 2000789842.

MNase titration reveals differences between nucleosome occupancy and chromatin accessibility

(Submitter supplied) Chromatin accessibility plays a fundamental role in gene regulation. One mechanism to regulate accessibility is nucleosome placement, which is often measured by quantifying protection of DNA from enzymatic digestion. We introduce a metric that uses micrococcal nuclease (MNase) digestion in a novel manner to measure chromatin accessibility by combining information from several digests of increasing depths. more...