GEO DataSet Links for SRA (Select 19185593) - GEO DataSets

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Items: 2

Select item 3058194221.

Peripheral T cells of patinet #12 before TTF treatment

Organism:: Homo sapiens

Source name:: Peripheral T lymphocytes isolated from PBMC

Platform:: GPL24676
Series:: GSE193729

Download data: TXT

Sample

Accession:: GSM5819422

ID:: 305819422

SRA Run Selector

Select item 2001937292.

TTFields treatment effects on newly diagnosed Glioblastoma patients in peripheral T lymphocytes

(Submitter supplied) We report the application of RNA-based sequencing technology for high-throughput profiling of T cell enriched peripheral blood mononuclear cells. By sequencing in total of 12 pairs GBM patient samples, we extracted TCRαβ V(D)J sequences from the deep RNA-seq of T cells isolated from the 24 PBMCs to determine if TTFields treatment affected TCR diversity, using the Simpson’s diversity index (DI), which is the average proportional abundance of TCR clones based on the weighted arithmetic mean. more...