GEO DataSet Links for SRA (Select 14093148) - GEO DataSets

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Links from SRA

Items: 2

Select item 3052442501.

NPcis Tumor 3 Grade III

Organism:: Mus musculus

Source name:: Tumor tissue

Platform:: GPL24247
Series:: GSE172221

Download data: TXT

Sample

Accession:: GSM5244250

ID:: 305244250

SRA Run Selector

Select item 2001722212.

A genetic mouse model of malignant peripheral nerve sheath tumor with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human tumors

(Submitter supplied) We established a new genetically engineered mouse (GEM) model of malignant peripheral nerve sheath tumors (MPNST) based on postnatal deletion of a Nf1;Trp53 cis-conditional allele by the tamoxifen-inducible Plp-CreER (NP-Plp). We also generated two Lats1;2 conditional knockout models by using Nestin-Cre (Lats-Nes) and Plp-CreER (Lats-Plp), both of which also develop tumors similar to MPNST (GEM-PNST). more...