GEO DataSet Links for SRA (Select 14068963) - GEO DataSets

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Items: 2

Select item 3052393231.

DHO2_1D

Organism:: Macaca mulatta

Source name:: Antigen presenting cell

Platform:: GPL23949
Series:: GSE171978

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Sample

Accession:: GSM5239323

ID:: 305239323

SRA Run Selector

Select item 2001719782.

Cytomegalovirus-mediated expansion of IL-15-responsive innate-memory cells with SIV killing function

(Submitter supplied) We investigated the effects of rhesus CMV (RhCMV) on composition and function of the immune system in young macaques. Within months of infection, RhCMV was associated with impressive changes in antigen presenting cells, T cells, and NK cells—and marked expansion of innate-memory CD8+ T cells. These cells express high levels of NKG2A/C and the IL-2- and IL-15-receptor beta chain, CD122. IL-15 was sufficient to drive differentiation of the cells in vitro and in vivo. more...