GEO DataSet Links for SRA (Select 13431877) - GEO DataSets

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Items: 2

Select item 3051514871.

intestinal stromal cells pre-capture [WTCHG_288196_207204]

Organism:: Homo sapiens

Source name:: colonic mucosa

Platform:: GPL20301
Series:: GSE168626 GSE168634

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Accession:: GSM5151487

ID:: 305151487

SRA Run Selector

Select item 2001686262.

Targeted single cell RNA-sequencing of transcription factors facilitates biological insights from human cell experimental models [intestinal stromal cells pre-capture]

(Submitter supplied) Single cell RNA sequencing (scRNA-seq) is a widely used method for identifying cell types and trajectories in biologically heterogeneous samples, but is limited in its detection and quantification of lowly expressed genes. This results in missing important biological signals, such as the expression of key transcription factors (TFs) driving cellular differentiation. We show that targeted sequencing of ~1000 TFs (scCapture-seq) in iPSC-derived neuronal cultures greatly improves the biological information garnered from scRNA-seq. more...