GEO DataSet Links for SRA (Select 13079709) - GEO DataSets

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Links from SRA

Items: 2

Select item 3050507901.

H4K16ac ChIP Input 3

Organism:: Drosophila melanogaster

Source name:: KC cells

Platform:: GPL19951
Series:: GSE165833

Download data: BW

Sample

Accession:: GSM5050790

ID:: 305050790

SRA Run Selector

Select item 2001658332.

Diverging principles of selective sex chromosome regulation during evolution of Drosophila

(Submitter supplied) The dosage compensation complex (DCC) of Drosophila identifies its X chromosomal binding sites with exquisite selectivity. The principles that assure this vital targeting are known from the D. melanogaster model: DCC-intrinsic specificity of DNA binding, cooperativity with the CLAMP protein, and non-coding roX2 RNA transcribed from the X chromosome. We found that in D. virilis, a species separated from melanogaster by 40 million years of evolution, all principles are active, but contribute differently to X-specificity. more...