GEO DataSet Links for SRA (Select 12444830) - GEO DataSets

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Items: 2

Select item 3049118271.

Cynomolgus_Macaque_Sample8-2

Organism:: Macaca fascicularis

Source name:: Cynomolgus_Macaque_Sample8

Platform:: GPL28212
Series:: GSE161645

Download data: MTX

Sample

Accession:: GSM4911827

ID:: 304911827

SRA Run Selector

Select item 2001616452.

scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution

(Submitter supplied) Adeno-associated virus (AAV)-mediated gene therapies are rapidly advancing to the clinic, and AAV engineering has resulted in vectors with increased ability to deliver therapeutic genes. Although the choice of vector is critical, quantitative comparison of AAVs, especially in large animals, remains challenging. Here, we developed an efficient single-cell AAV engineering pipeline (scAAVengr) to simultaneously quantify and rank efficiency of competing AAV vectors across all cell types in the same animal. more...