GEO DataSet Links for SRA (Select 12331029) - GEO DataSets

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Items: 2

Select item 3048804731.

OSC H3K4me2 si-ctp rep2

Organism:: Drosophila melanogaster

Source name:: Ovarian somatic cells (OSC)

Platform:: GPL21306
Series:: GSE160855 GSE160860

Download data: BW

Sample

Accession:: GSM4880473

ID:: 304880473

SRA Run Selector

Select item 2001608552.

Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila [ChIP-Seq]

(Submitter supplied) In animal gonads, the PIWI-interacting RNA (piRNA) pathway guards genome integrity in part through the co-transcriptional gene silencing of transposon insertions. In Drosophila ovaries, piRNA-loaded Piwi detects nascent transposon transcripts and instructs heterochromatin formation through the Panoramix-induced co-transcriptional silencing (PICTS) complex, containing Panoramix, Nxf2 and Nxt1. Here, we report that the highly conserved dynein light chain LC8/Cut-up (Ctp) is an essential component of the PICTS complex. more...