GEO DataSet Links for SRA (Select 1093954) - GEO DataSets

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Items: 2

Select item 3015422701.

Sample_LSD1_SH-SY5Y_B0_S63

Organism:: Homo sapiens

Source name:: Cultured SH-SY5Y cells

Platform:: GPL16791
Series:: GSE58258 GSE63153

Download data: BEDGRAPH

Sample

Accession:: GSM1542270

ID:: 301542270

SRA Run Selector

Select item 2000582582.

The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation [ChIP-Seq]

(Submitter supplied) During brain development, histone-modifying enzymes play an important role by orchestrating transcriptional programs that regulate neuronal maturation. Lysine-Specific Demethylase 1 (LSD1, also named as KDM1A) functions as a transcriptional repressor by removing methyl groups at lysine 4 of histone H3 (H3K4). In neurons, alternative splicing can include an additional exon (exon E8a) within LSD1 transcripts, generating a LSD1+8a neuro-specific isoform. more...