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Genome-wide maps of R-loops in Drosophila embryogenesis and cultured cells

(Submitter supplied) We report the genome localization of R-loops in early and late-stage embryos relative to Drosophila cultured cells. We demonstrate that proper absolute R-loop levels chage during embryogenesis and that resolution of R-loops is critical for embryonic development. R-loop mapping by strand-specific DRIP-seq revealed that R-loop localization is plastic across development, both in the genes which form R-loops and where they localize relative to gene bodies. more...
Organism:
Drosophila melanogaster
Type:
Other
Platform:
GPL25244
15 Samples
Download data: BED
Series
Accession:
GSE185403
ID:
200185403

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