GEO DataSet Links for PMC (Select 8672788) - GEO DataSets

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Items: 2

Select item 2001862551.

a-Synuclein Antisense Transcript SNCA-AS1 regulates synapses- and aging-related genes suggesting its implication in Parkinson’s Disease

(Submitter supplied) SNCA protein product, a-synuclein, is widely renowned for its role in synaptogenesis and implication in both aging and Parkinson’s Disease (PD), but research efforts are still needed to elucidate its physiological functions and mechanisms of regulation. In this work, we aim to characterize SNCA-AS1, antisense transcript to the SNCA gene, and its implications in cellular processes. The overexpression of SNCA-AS1 upregulates both SNCA and a-synuclein, and through RNA-seq analysis we investigated the transcriptomic changes of which both genes are responsible. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
8 Samples

Download data: RESULTS

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Accession:: GSE186255

ID:: 200186255

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001834102.

MINCR: a Long non-coding RNA shared between cancer and neurodegeneration

(Submitter supplied) Investigating MINCR potential mechanisms of action and its implications in cancer and neurodegeneration in relation to its expression levels in SH-SY5Y cells through RNA-seq approach.