GEO DataSet Links for PMC (Select 8316553) - GEO DataSets

Select item 2001450921.

Intron looping is mediated by U1 snRNP and RNA polymerase II co-transcriptionally

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
18 Samples

Download data: BEDGRAPH, BW, TXT

Series

Accession:: GSE145092

ID:: 200145092

PubMed Full text in PMC Similar studies

Select item 2001449062.

Intron looping is mediated during transcription by U1 snRNP and RNA polymerase II [RNA-Seq]

(Submitter supplied) In the earliest step of spliceosome assembly, the two splice sites flanking an intron are brought into proximity by U1 snRNP and U2AF. The mechanism that facilitates this intron looping is poorly understood. Using a CRISPR interference-based approach to halt RNA polymerase II transcription in the middle of introns, we discovered that the 5 splice site base pairs with a U1 snRNA that is tethered to RNA polymerase II during intron synthesis. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
1 Sample

Download data: TXT

Series

Accession:: GSE144906

ID:: 200144906

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001449053.

Intron looping is mediated during transcription by U1 snRNP and RNA polymerase II [RIP-seq]

(Submitter supplied) In the earliest step of spliceosome assembly, the two splice sites flanking an intron are brought into proximity by U1 snRNP and U2AF. The mechanism that facilitates this intron looping is poorly understood. Using a CRISPR interference-based approach to halt RNA polymerase II transcription in the middle of introns, we discovered that the 5 splice site base pairs with a U1 snRNA that is tethered to RNA polymerase II during intron synthesis. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
10 Samples

Download data: BEDGRAPH, BW

Series

Accession:: GSE144905

ID:: 200144905

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001448744.

Intron looping is mediated by U1 snRNP and RNA polymerase II co-transcriptionally [ChIP-seq]

(Submitter supplied) In the earliest step of spliceosome assembly, the two splice sites flanking an intron are brought into proximity by U1 snRNP and U2AF. The mechanism that facilitates this intron looping is poorly understood. Using a CRISPR interference-based approach to halt RNA polymerase II transcription in the middle of introns, we discovered that the 5 splice site base pairs with a U1 snRNA that is tethered to RNA polymerase II during intron synthesis. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
7 Samples

Download data: BW

Series

Accession:: GSE144874

ID:: 200144874

PubMed Full text in PMC Similar studies SRA Run Selector

GEO DataSets

Functional Genomics Studies

Result Filters

Entry type

Organism

Study type

Author

Attribute name

Publication dates

Custom date range

Additional filters

Send to:

Links from PMC

Items: 4

Send to:

Supplemental Content

Find related data

Important Links

Recent activity