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cis-regulatory logic of Shh expression reveals common history of unpaired and paired fins

(Submitter supplied) Despite their evolutionary, developmental, and functional importance the origin of vertebrate paired appendages remains a mystery. Classical ideas center on three hypotheses: that paired fins relate to gill arches, are derived from a fin fold, or that median fins evolved first and paired fins arose by co-option of ancient genetic patterning modules. Importantly, the third hypothesis makes specific predictions about the function and phylogenetic history of cis-regulatory elements (CREs) involved in appendage patterning. more...
Organism:
Oryzias latipes; Mus musculus
Type:
Other
Platforms:
GPL17021 GPL23308
4 Samples
Download data: BEDGRAPH
Series
Accession:
GSE97860
ID:
200097860

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