GEO DataSet Links for PMC (Select 5223503) - GEO DataSets

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Items: 3

Select item 2000665101.

Transcriptome analysis of Sch9-depedent thermotolerance mechanism reveals a dual functional heat shock transcription factor, Hsf1, in Cryptococcus neoformans

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Cryptococcus neoformans var. neoformans JEC21; Cryptococcus neoformans var. grubii

Type:: Expression profiling by array

Platform:: GPL8638
42 Samples

Download data: GPR

Series

Accession:: GSE66510

ID:: 200066510

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000665092.

Transcriptome analysis of Sch9-depedent thermotolerance mechanism reveals a dual functional heat shock transcription factor, Hsf1, in Cryptococcus neoformans [HSF1 overexpression]

(Submitter supplied) Thermotolerance is a crucial virulence attribute for Cryptococcus neoformans, which causes fatal fungal meningitis in humans. A protein kinase, Sch9, suppresses the thermotolerance of C. neoformans but its regulatory mechanism remains unknown. Here we elucidated the Sch9-dependent and -independent signaling networks for modulating the thermotolerance of C. neoformans through a genome-wide transcriptome analysis and reverse genetics approaches. more...