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Items: 3

1.

Geminin regulates the transcriptional and epigenetic status of neuronal fate promoting genes during mammalian neurogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Xenopus laevis; Mus musculus
Type:
Expression profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL13112 GPL1318
10 Samples
Download data: CEL, TXT
Series
Accession:
GSE39673
ID:
200039673
2.

Regulation of neurogenin-dependent gene expression by geminin

(Submitter supplied) Transcriptional targets of neurogenin (Ngnr1) were identified by over-expression of an inducible form of neurogenin in Xenopus ectodermal explants. The effects of co-expressing the nucleoprotein geminin on Ngnr1-dependent target gene transactivation were defined. Regulating the transition from lineage-restricted progenitors to terminally differentiated cells is a central aspect of nervous system development. more...
Organism:
Xenopus laevis
Type:
Expression profiling by array
Platform:
GPL1318
6 Samples
Download data: CEL
Series
Accession:
GSE39658
ID:
200039658
3.

Geminin knockdown in embryonic stem cell-derived neural precursors

(Submitter supplied) Regulating the transition from lineage-restricted progenitors to terminally differentiated cells is a central aspect of nervous system development. Here, we investigated the role of the nucleoprotein Geminin in regulating neurogenesis at a mechanistic level during both Xenopus primary neurogenesis and mammalian neuronal differentiation in vitro. The latter work utilized both neural cells derived from embryonic stem and embryonal carcinoma cells in vitro and neural stem cells from mouse forebrain. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
4 Samples
Download data: TXT
Series
Accession:
GSE39657
ID:
200039657
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