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Items: 2

1.

Expression data from human bone marrow hematopoietic stem cells

(Submitter supplied) In the human hematopoietic system, aging is associated with decreased bone marrow cellularity, decreased adaptive immune system function, and increased incidence of anemia and other hematological disorders and malignancies. Recent studies in mice suggest that changes within the hematopoietic stem cell (HSC) population during aging contribute significantly to the manifestation of these age-associated hematopoietic pathologies. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3942
Platform:
GPL570
27 Samples
Download data: CEL
Series
Accession:
GSE32719
ID:
200032719
2.
Full record GDS3942

Aging effect on bone marrow hematopoietic stem cells

Analysis of bone marrow-derived, hematopoietic stem cells (HSC) from healthy, hematologically normal young and elderly donors. Aged HSCs are increased in frequency and are less quiescent than young HSCs. Results provide insight into molecular mechanisms underlying the hematopoietic aging phenotype.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 age sets
Platform:
GPL570
Series:
GSE32719
27 Samples
Download data: CEL

Supplemental Content

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