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Items: 2

1.

Gene expression data from temporal cortex of young adult, old and AD-like Microcebus murinus

(Submitter supplied) Aging is the primary risk factor of neurodegenerative disorders such as Alzheimer's disease (AD). However, the molecular events occurring during brain aging are extremely complex and still largely unknown. For a better understanding of these age-associated modifications, animal models as close as possible to humans are needed. We thus analyzed the transcriptome of the temporal cortex of the primate Microcebus murinus using human oligonucleotide microarrays (Affymetrix). more...
Organism:
Microcebus murinus; Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4128
Platform:
GPL570
18 Samples
Download data: CEL, CHP
Series
Accession:
GSE21779
ID:
200021779
2.
Full record GDS4128

Model of cerebral aging and Alzheimer's disease: temporal cortex

Analysis of temporal cortex of young adult, old healthy, and Alzheimer’s disease (AD-like) animals. AD-like animals presented ß-amyloid plaques and cortical atrophy, which are signs of AD in humans. Results provided insight into molecular basis of physiological versus pathological brain aging.
Organism:
Homo sapiens; Microcebus murinus
Type:
Expression profiling by array, count, 2 age, 2 disease state, 2 gender sets
Platform:
GPL570
Series:
GSE21779
18 Samples
Download data: CEL, CHP

Supplemental Content

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