GEO DataSet Links for PMC (Select 2194763) - GEO DataSets

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Items: 2

Select item 2000068001.

Effects of Cimicfuga racemosa (black cohosh) in MCF-7 cells

(Submitter supplied) Extracts from the rhizome of Cimicifuga racemosa (black cohosh) are increasingly popular as herbal alternative to hormone replacement therapy (HRT) for the alleviation of postmenopausal disorders. However, the molecular mode of action and the active principles are presently not clear. Previously published data have been largely contradictory. We, therefore, investigated the effects of a lipophilic Cimicifuga rhizome extract on the ER+ breast cancer MCF-7 cells at transcriptional level in comparision to 17beta-estradiol and the ER antagonist tamoxifen. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3105
Platform:: GPL570
8 Samples

Download data: CEL

Series

Accession:: GSE6800

ID:: 200006800

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 31052.

Cimicifuga racemosa extract effect on breast cancer cell line MCF-7

Analysis of MCF-7 breast cancer cells treated with a Cimicifuga racemosa extract. Extracts from the C. racemosa rhizome are used as an herbal alternative to hormone replacement therapy for alleviation of postmenopausal disorders. Results provide insight into the extract's molecular mode of action.