GEO DataSet Links for PMC (Select 1899882) - GEO DataSets

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Items: 2

Select item 2000055101.

Expression data from wild type and Taf7l mutant testes

(Submitter supplied) TFIID is a general transcription factor required for transcription of most protein-coding genes by RNA polymerase II. TAF7L is an X-linked germ cell-specific paralogue of TAF7, which is a generally expressed component of TFIID. Here we report the generation of Taf7l mutant mice by homologous recombination in embryonic stem cells using the Cre-loxP strategy. While spermatogenesis is completed in Taf7l mutant mice, the weight of Taf7l mutant testis is decreased and the amount of sperm in the epididymis is sharply reduced. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2857
Platform:: GPL1261
4 Samples

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Accession:: GSE5510

ID:: 200005510

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 28572.

Taf7l deficiency effect on the testis

Analysis of testes of animals lacking Taf7l. TAF7L is an X-linked germ cell-specific paralog of TAF7, which is a generally expressed component of TFIID. Results provide insight into the role of Taf7l in spermatogenesis.