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Full record GDS4305

Glycogen synthase kinase 3 α knockdown in acute myeloid leukemia cell lines

Analysis of AML cell lines infected with shRNAs against glycogen synthase kinase 3 α and β isoforms (GSK-3α, GSK-3β). GSK-3 is a multifunctional serine threonine kinase; specific loss of GSK-3α induces differentiation in AML. Results provide insight into the role of GSK-3α in AML.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 cell line, 3 genotype/variation, 5 other sets
Platform:
GPL3921
Series:
GSE35200
44 Samples
Download data: CEL

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