Gamma secretase inhibitor MRK-003 effect on pancreatic ductal adenocarcinoma tumor xenografts - - GEO DataSets

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Gamma secretase inhibitor MRK-003 effect on pancreatic ductal adenocarcinoma tumor xenografts

Analysis of 9 individual patient-derived, pancreatic ductal adenocarcinoma (PDAC) xenografts treated with GSI MRK-003. MRK-003 monotherapy significantly reduced tumor volume in 5 of 9 xenografts. Results provide insight into the molecular basis of MRK-003-mediated attenuation of PDAC.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 9 cell line, 2 other sets

Platform:: GPL570
Series:: GSE37645
18 Samples

Download data: CEL

DataSet

Accession:: GDS4342

ID:: 4342

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Gamma secretase inhibitor MRK-003 effect on pancreatic ductal adenocarcinoma tum...
Gamma secretase inhibitor MRK-003 effect on pancreatic ductal adenocarcinoma tumor xenografts
Accession: GDS4342

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Genes with a similar H3K4me3 profile for Gene (Select 1813) (13)
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Eulemur cytochrome oxidase subunit III (COIII) gene, partial cds; tRNA-Gly gene,...
Eulemur cytochrome oxidase subunit III (COIII) gene, partial cds; tRNA-Gly gene, complete sequence; NADH dehydrogenase subunit 3 (ND3) gene, complete cds; tRNA-Arg gene, complete sequence; NADH dehydrogenase subunit 4L (ND4L) and NADH dehydrogenase subunit 4 (ND4) genes, complete cds; and tRNA-His, tRNA-Ser, and tRNA-Leu genes, complete sequence; mitochondrial.
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