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Full record GDS4303

Notch1 overexpression model of T-cell acute lymphoblastic leukemia: double positive CD4+/8+ cells

Analysis of DP (CD4+/8+) cells from an intracellular Notch1 (Notch1-IC)-induced T-ALL model that recapitulates most features of human T-ALL. T-ALL malignancy is driven by oncogenic activation of NOTCH1 signaling. Results provide insight into the molecular basis of Notch1-driven leukemogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL1261
Series:
GSE34554
4 Samples
Download data: CEL
DataSet
Accession:
GDS4303
ID:
4303

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