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Full record GDS4135

Postmortem temporal cortex from Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort: astrocytes

Analysis of GFAP+ astrocytes representing different Braak stages and ApoE genotypes, in post-mortem temporal cortex samples. Astrocytes synthesize ApoE, which is involved in the astrocytic clearance of aggregated β-amyloid plaques. Results provide insight into role of ApoE in Alzheimer's pathology.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state, 2 genotype/variation sets
Platform:
GPL570
Series:
GSE29652
18 Samples
Download data: CEL
DataSet
Accession:
GDS4135
ID:
4135

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