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Full record GDS3800

von Hippel-Lindau (VHL) tumor suppressor protein deficiency effect on pancreatic islet cells

Analysis of pancreatic islet cells deficient for the von Hippel-Lindau tumor suppressor protein from 18 to 26 wk-old animals. Loss of Vhlh in beta-cells leads to impaired glucose tolerance and to abnormal insulin secretion. Results provide insight into the role of Vhlh in pancreatic beta cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age, 2 gender, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE11484
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3800
ID:
3800

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