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Full record GDS3582

PTEN heterozygosity effect on Smoothened-active mouse model

Analysis of medulloblastoma (MB) tumors from mice heterozygous for PTEN. SmoA1 +; Pten +/- mice exhibited decreased survival, an increased incidence, and a shorter time to onset of symptoms, compared to SmoA1 +; Pten +/+ mice. Results provide insight into the role of PTEN in the pathogenesis of MB.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL6887
Series:: GSE19059
12 Samples

Download data: TXT

DataSet

Accession:: GDS3582

ID:: 3582

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