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Full record GDS1346

Bruton's tyrosine kinase mutant models of X-linked agammaglobulinemia

Analysis of splenic B cells from mutants with a knockout of Bruton's tyrosine kinase (Btk) or a R28C missense mutation in Btk. Btk mutations cause a block in B cell differentiation and lead to X-linked agammaglobulinemia (XLA). Results provide insight into the pathogenesis of XLA.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 genotype/variation sets
Platform:
GPL81
Series:
GSE2826
6 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS1346
ID:
1346

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