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Full record GDS5421

Transcription factor E2-2 haplodeficiency effect on systemic lupus erythematosus model: splenocytes

Analysis of splenocytes from WT, B6.Sle1.Sle3 (lupus mice) and B6.Sle1.Sle3 Tcf4+/− (Sle/het) mice haplodeficient for the transcription factor E2-2 (Tcf4). E2-2 is a specific regulator of plasmacytoid dendritic cell (pDC) development. Results provide insight into role of pDC in SLE pathogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 genotype/variation sets
Platform:
GPL6246
Series:
GSE57324
8 Samples
Download data: CEL
DataSet
Accession:
GDS5421
ID:
5421

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