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Full record GDS5064

Neuroserpin G392E mutant expression

Analysis of HeLa cells expressing the G392E mutant of neuroserpin. Accumulation of mutant neuroserpin polymers in the ER is associated with familial encephalopathy with neuroserpin inclusion bodies. Results provide insight into pathways initiated by the polymerization of neuroserpin within the ER.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 4 genotype/variation sets
Platform:
GPL10558
Series:
GSE46230
24 Samples
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