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Full record GDS4965

Bedaquiline treatment: time course

Analysis of Mycobacterium tuberculosis treated with Bedaquiline (BDQ; Sirturo) and harvested up to 360 min after drug addition. BDQ, an ATP synthase inhibitor, causes bacteriostasis within hours of treatment. Results provide insight into molecular mechanisms underlying BDQ-induced bacterial killing.
Organism:
Mycobacterium tuberculosis H37Rv
Type:
Expression profiling by array, transformed count, 5 time sets
Platform:
GPL4519
Series:
GSE43749
17 Samples
Download data: CEL

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