GEO DataSets

Analysis of fat from abdominal surgical incisions made using two different methods: electrosurgery (ES) and ultrasonic Harmonic blade (HB). Ultrasonic devices offer better coagulation with less tissue damage. Results provide insight into the differences between ES and HB at a molecular level.

Organism:

Sus scrofa

Type:

Expression profiling by array, transformed count, 3 protocol sets

Platform:

GPL3533

Series:

GSE47710

12 Samples

Download data: CEL

(Submitter supplied) This study compares the gene expression changes in Sus scrofa in response to two different methods for abdominal surgical incisions ; electrosurgery and harmonic blade. As the use of laparoscopic surgery has become more widespread in recent years, the need has increased for minimally-invasive surgical devices that effectively cut and coagulate tissue with reduced tissue trauma. Although electrosurgery (ES) has been used for many generations, newly-developed ultrasonic devices (HARMONIC® Blade, HB) have been shown at a macroscopic level to offer better coagulation with less thermally-induced tissue damage. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Dataset:

GDS4900

Platform:

GPL3533

12 Samples

Download data: CEL

(Submitter supplied) Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of liver disease affecting 20-30% of the population in developed countries. NAFLD is strongly associated with abdominal obesity and is recognized as the hepatic manifestation of the metabolic syndrome. In a subgroup of patients with NAFLD inflammation and fibrosis develops, this so-called Non-Alcoholic Steatohepatitis (NASH) may progress to cirrhosis and hepatocellular carcinoma. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15207

15 Samples

Download data: CEL

(Submitter supplied) Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of liver disease affecting 20-30% of the population in developed countries. NAFLD is strongly associated with abdominal obesity and is recognized as the hepatic manifestation of the metabolic syndrome. In a subgroup of patients with NAFLD inflammation and fibrosis develops, this so-called Non-Alcoholic Steatohepatitis (NASH) may progress to cirrhosis and hepatocellular carcinoma. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15207

53 Samples

Download data: CEL

(Submitter supplied) Previously, we developed a new model of diabetes-induced wound healing impairment in skin-humanized mice models that faithfully recapitulates the major histo-physiological features of such skin repair-deficient condition. Aiming to dissect the molecular mechanisms responsible for the delayed wound closure, global gene expression studies were performed.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL571

26 Samples

Download data: CEL, CHP

(Submitter supplied) In this study we performed transcriptome sequencing on the Subcutaneous Adipose Tissue and Epicardial Adipose Tissue of both diabetic and nondiabetic human patients.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL11154

16 Samples

Download data: CSV