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Links from GEO DataSets

Items: 20

1.
Full record GDS473

Muscle function and aging - female (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (20-29 year old) and older (65-71 year old) women
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL97
Series:
GSE674
15 Samples
Download data
DataSet
Accession:
GDS473
ID:
473
2.

Normal Muscle - Female , Effect of Age

(Submitter supplied) Healthy younger (20-29 yr) and older (65-71 yr) women donated vastus lateralis muscle under standard conditions. Keywords = muscle Keywords = aging Keywords: time-course
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS472 GDS473
Platforms:
GPL97 GPL96
30 Samples
Download data
Series
Accession:
GSE674
ID:
200000674
3.
Full record GDS472

Muscle function and aging - female (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (20-29 year old) and older (65-71 year old) women
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL96
Series:
GSE674
15 Samples
Download data
DataSet
Accession:
GDS472
ID:
472
4.

Normal human muscle - U133 arrays

(Submitter supplied) vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old) Keywords = muscle Keywords = aging Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS287 GDS288
Platforms:
GPL96 GPL97
30 Samples
Download data
Series
Accession:
GSE362
ID:
200000362
5.
Full record GDS288

Muscle function and aging - male (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL97
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS288
ID:
288
6.
Full record GDS287

Muscle function and aging - male (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL96
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS287
ID:
287
7.

Young and old muscle comparison

(Submitter supplied) RNA was pooled from vastus lateralis biopsies obtained from 8 younger (21-24 yr) and 8 older (66-77 yr)men. Healthy subjects with no neuromuscular disease. Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
2 Samples
Download data
Series
Accession:
GSE17
ID:
200000017
8.

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans

(Submitter supplied) The aim of the study was to investigate how short-term fasting affects whole-body energy homeostasis and skeletal muscle energy/nutrient-sensing pathways and transcriptome in humans. For this purpose, twelve young healthy men were studied during a 24-hour fast. Skeletal muscle biopsies were collected and analyzed at baseline and after 4, 10 and 24h of fasting. As expected, fasting induced a time-dependent decrease in plasma insulin and leptin levels, whereas levels of ketone bodies and free fatty acids increased. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5473
Platform:
GPL10558
48 Samples
Download data: TXT
Series
Accession:
GSE55924
ID:
200055924
9.
Full record GDS5473

Short-term fasting effect on skeletal muscle: time course

Analysis of skeletal muscle biopsies collected at 1.5, 4, 10, and 24hr post-meal time from healthy young men subjected to a 24hr fast. Results provide insight into the molecular mechanisms underlying metabolic adaptation to fasting in healthy humans.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 12 individual, 4 time sets
Platform:
GPL10558
Series:
GSE55924
48 Samples
Download data
DataSet
Accession:
GDS5473
ID:
5473
10.

Effect of Oxandrolone on Muscle in Duchenne Muscular Dystrophy

(Submitter supplied) Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were then treated for 3 months with oxandrolone (a synthetic anabolic steroid, 0.1 mg/kg/day) and the studies repeated. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1333 GDS1334
Platforms:
GPL96 GPL97
12 Samples
Download data
Series
Accession:
GSE1764
ID:
200001764
11.
Full record GDS1334

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133B)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL97
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1334
ID:
1334
12.
Full record GDS1333

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL96
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1333
ID:
1333
13.

Resistance Exercise Reverses Aging in Human Skeletal Muscle

(Submitter supplied) Human aging is associated with skeletal muscle atrophy and functional impairment (sarcopenia). Multiple lines of evidence suggest that mitochondrial dysfunction is a major contributor to sarcopenia. We evaluated whether healthy aging was associated with a transcriptional profile reflecting mitochondrial impairment and whether resistance exercise could reverse this signature to that approximating a younger physiological age. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL2700
65 Samples
Download data: CSV
Series
Accession:
GSE8479
ID:
200008479
14.

Effect of age on skeletal muscle

(Submitter supplied) Comparison of gene expression in young soleus muscle (3-4 months) with old soleus muscle (30-31 months). Keywords: parallel sample
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platforms:
GPL85 GPL86 GPL87
296 Samples
Download data
Series
Accession:
GSE353
ID:
200000353
15.

The effect of age on the skeletal muscle transcriptome during hypertrophy

(Submitter supplied) Transcriptome analysis of skeletal muscle during hypertrophic growth in aged mice Global gene expression patterns were determined from microarray results on day 1, 3, 5, 7, 10 and 14 during plantaris muscle hypertrophy induced by synergist ablation in old adult mice (25 months).
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
14 Samples
Download data: CEL, CHP
Series
Accession:
GSE67160
ID:
200067160
16.

Expression data during plantaris muscle hypertrophy induced by synergist ablation in young adult mice

(Submitter supplied) Global gene expression patterns were determined from microarray results on day 1, 3, 5, 7, 10 and 14 during plantaris muscle hypertrophy induced by synergist ablation in young adult mice (5 months).
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4932
Platform:
GPL6246
14 Samples
Download data: CEL
Series
Accession:
GSE47098
ID:
200047098
17.
Full record GDS4932

Synergist ablation effect on young adult plantaris muscle: time course

Analysis of right and left plantaris muscle from young males (5 months old) subjected to 1, 3, 5, 7, 10 and 14 days of synergist ablation surgery to induce hypertrophy. Results provide insight into the molecular response of young skeletal muscle to mechanical overload induced by synergist ablation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 stress, 7 time, 2 tissue sets
Platform:
GPL6246
Series:
GSE47098
14 Samples
Download data: CEL
18.

Sex and aging effect on skeletal muscle transcriptome in humans

(Submitter supplied) The aim of this investigation was to develop a global view of muscle transcriptional differences between older men and women and with aging for each sex.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4858
Platform:
GPL570
22 Samples
Download data: CEL
Series
Accession:
GSE38718
ID:
200038718
19.
Full record GDS4858

Skeletal muscles from men and women of various ages

Analysis of biceps brachii muscles from men and women 19 to 28 or 65 to 76 years of age. Results provide insight into the influence of gender on age-related changes in the molecular properties of the skeletal muscle.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 age, 2 gender sets
Platform:
GPL570
Series:
GSE38718
22 Samples
Download data: CEL
20.

Gene regulation in gastrocnemius muscle of denervated mouse with HDAC4 inducible knockout or class IIa HDAC inhibitior NVS-HD1 treatment

(Submitter supplied) Our class IIa HDAC inhibitor, NVS-HD1, inhibited HDAC4 with less than 1 nM potency while exhibiting >200 fold selectivity on class IIa HDACs compared to class I (HDAC1, 3, 8) and class IIb (HDAC6) HDACs, making it the most potent and selective class IIa HDAC inhibitor reported so far. We tested the efficacy of NVS-HD1 in the mouse denervation model, either alone or on the genetic background of HDAC4 whole-body inducible knockout (HDAC4 iRKO). more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
34 Samples
Download data: BW, TXT
Series
Accession:
GSE136627
ID:
200136627
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