GEO DataSets

Analysis of minor salivary glands with varying degrees of inflammation from Sjögren's syndrome (SS) patients. SS is a chronic autoimmune disease targeting salivary and lacrimal exocrine glands. Results provide insight into the molecular mechanisms underlying the immunopathology associated with SS.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 5 disease state sets

Platform:

GPL570

Series:

GSE23117

15 Samples

Download data: CEL

(Submitter supplied) To study the gene expression profile of salivary glands with varying degrees of inflammation in Sjogren's and non Sjogren's patients

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3940

Platform:

GPL570

15 Samples

Download data: CEL

(Submitter supplied) Macrophages are critical regulators of immune responses, and link innate immunity to acquired immunity. The precise mechanism of the pathogenesis of autoimmune diseases through tissue-resident macrophage is unclear. The role of the tissue-resident macrophages in the onset or development of autoimmunity was investigated using a murine model for Sjögren’s syndrome.

Organism:

Mus musculus

Type:

Expression profiling by RT-PCR

Platform:

GPL24623

2 Samples

Download data: XLS

(Submitter supplied) <Objective> To compare gene expression in labial salivary glands (LSG) of IgG4-related disease (IgG4-RD) with Sjögren’s syndrome (SS). <Methods> Gene expression was analyzed by DNA microarray in LSG of IgG4-RD (n=5), SS (n=5), and healthy controls (n=3). Differentially expressed genes (DEGs) in IgG4-RD and SS were identified, and gene-annotation enrichment analysis of these DEGs was performed using Gene Ontology (GO) annotation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

13 Samples

Download data: CEL