Similar studies for GEO DataSets (Select 3883) - GEO DataSets

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Items: 2

Select item 38831.

Type 2 diabetes and role of hepatokines

Analysis of percutaneous needle liver biopsies from 10 people with type 2 diabetes (T2D) and 7 normal subjects. The liver has a central role in glucose homeostasis and is a major site of secretory protein production. Results provide insight into the role of hepatokines in T2D insulin resistance.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 2 gender sets

Platform:: GPL570
Series:: GSE23343
17 Samples

Download data: CEL

DataSet

Accession:: GDS3883

ID:: 3883

Select item 2000233432.

Expression data from human liver with or without type 2 diabetes

(Submitter supplied) The liver may regulate glucose homeostasis by modulating the sensitivity/resistance of peripheral tissues to insulin, by way of the production of secreted proteins, termed hepatokines. To identify hepatic secretory proteins involved in insulin resistance, we performed liver biopsies in humans with or without type 2 diabetes and conducted a comprehensive analysis of gene expression profiles.