Similar studies for GEO DataSets (Select 3661) - GEO DataSets

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Items: 2

Select item 36611.

Hypertensive heart failure model

Analysis of heart from age-matched, spontaneously hypertensive animals with and without heart failure (HF). Results provide insight into the molecular mechanisms underlying the transition to hypertensive HF.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL1355
Series:: GSE19210
12 Samples

Download data: CEL

DataSet

Accession:: GDS3661

ID:: 3661

Select item 2000192102.

Transition from Compensated Hypertrophy to Systolic Heart Failure in the Spontaneously Hypertensive Rat

(Submitter supplied) Full Title: Transition from Compensated Hypertrophy to Systolic Heart Failure in the Spontaneously Hypertensive Rat: Structure, Function, and Transcript Analysis Gene expression changes and left ventricular remodeling associated with the transition to systolic heart failure (HF) were determined in the spontaneously hypertensive rat (SHR). By combining transcriptomics of left ventricles from six SHR with HF with changes in function and structure we aimed to better understand the molecular events underlying the onset of systolic HF compared to six age-matched, SHR with compensated hypertrophy. more...