Similar studies for GEO DataSets (Select 3435) - GEO DataSets

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Items: 2

Select item 34351.

Vancomycin effect on the kidney: dose response

Analysis of kidneys of BALB/c females treated with vancomycin (VA) for up to 400 mg/kg delivered intraperitoneally or intravenously. VA, an antibiotic treatment against methicillin-resistant Staphylococcus aureus, is nephrotoxic. Results provide insight into the molecular basis of VA nephrotoxicity.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 4 dose, 2 protocol sets

Platform:: GPL1261
Series:: GSE7793
48 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3435

ID:: 3435

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000077932.

Vancomycin nephrotoxicity assessed by DNA microarray

(Submitter supplied) The glycopeptide antibiotic vancomycin (VCM) represents one of the last lines of defense against methicillin-resistant Staphylococcus aureus infections. However, vancomycin is nephrotoxic, but the mechanism of toxicity is still unclear. The goal of this study was twofold: (1) gain insights into the molecular mechanisms of vancomycin nephrotoxicity at the genomic level and (2) evaluate potential biomarkers (gene expression profiles) of vancomycin-induced kidney injury Keywords: Dose response