Similar studies for GEO DataSets (Select 3388) - GEO DataSets

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Items: 2

Select item 33881.

Bisphenol A effect on nonmalignant breast epithelial cell aspirates from breast cancer patients

Analysis of random periareolar fine-needle aspirates collected from unafflicted, contralateral breast tissue of breast cancer patients and treated with bisphenol A (BPA). BPA is a prevalent xenoestrogen. Results provide insight into early molecular events induced by BPA in susceptible breast tissue.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent, 8 individual sets

Platform:: GPL570
Series:: GSE10270
24 Samples

Download data: CEL

DataSet

Accession:: GDS3388

ID:: 3388

Select item 2000102702.

Bisphenol A induces a profile of tumor aggressiveness in high-risk cells of breast cancer patients

(Submitter supplied) Breast cancer outcome is highly variable. Whether inadvertent exposure to environmental xenobiotics evokes a biological response promoting cancer aggressiveness and a higher probability of tumor recurrence remains unknown. To determine specific molecular alterations, which arise in high-risk breast tissue in the presence of the ubiquitous xenoestrogen, bisphenol A (BPA), we employed non-malignant random periareolar fine needle aspirates (RPFNA) in a novel functional assay. more...