Similar studies for GEO DataSets (Select 3129) - GEO DataSets

Select item 31291.

Parkinson's disease: substantia nigra (HG-U133B)

Analysis of medial and lateral substantia nigras (SNs) from post-mortem brain samples obtained from individuals with sporadic Parkinson's disease (PD). The SN exhibits extensive tissue damage in PD. Results provide insight into the pathogenesis of PD.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 23 individual, 3 tissue sets

Platform:: GPL97
Series:: GSE8397
47 Samples

Download data: CEL

DataSet

Accession:: GDS3129

ID:: 3129

Select item 2000083972.

Expression profiling of the Parkinsonian Brain

(Submitter supplied) Affymetrix HG_U133 array sets (A and B chips) were used to determine the whole genome transcription profile of clinically documented and neuropathologically confirmed cases of sporadic Parkinson's disease as well as controls. Keywords: disease-state analysis

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS3128 GDS3129
Platforms:: GPL97 GPL96
94 Samples

Download data: CEL

Series

Accession:: GSE8397

ID:: 200008397

Select item 31283.

Parkinson's disease: substantia nigra (HG-U133A)

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 23 individual, 3 tissue sets

Platform:: GPL96
Series:: GSE8397
47 Samples

Download data: CEL

DataSet

Accession:: GDS3128

ID:: 3128

Select item 2001366664.

Transcriptomic profiling of substantia nigra and putamen in Parkinson’s disease

(Submitter supplied) We report RNA sequencing results of human substantia nigra and putamen samples from Parkinson's disease patients and controls. Each substantia nigra sample is the result of pooling brain tissue from two individuals with the same , while each putamen sample is the result of pooling brain tissue from three individuals. We found 354 differentially expressed genes (DEGs) in the SN of PD patients compared to age-matched controls, while we observed 261 DEGs in the putamen samples. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
16 Samples

Download data: TXT

Series

Accession:: GSE136666

ID:: 200136666

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000188385.

Gene Expression in the Blood of Parkinson's Disease Patients

(Submitter supplied) Peripheral blood was collected from 18 Parkinson's Disease (PD) patients and 12 healthy controls (Ctrls). Total RNA was isolated and hybridized onto Affymetrix Exon_ST1 arrays to find in PDs versus controls: 1) genes that are differentiallly expressed and 2) genes with differential exonic expression (alternative splicing).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL5175
28 Samples

Download data: CEL, TXT

Series

Accession:: GSE18838

ID:: 200018838

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000259316.

Gene Expression Profiling of Human Embryonic Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra

(Submitter supplied) Our goal was to develop a list of genes that could be used effectively to highlight the genomic profiling of human embryonic neural stem cells (hENSCs), and to identify genes involved in the process of their differentiation to dopaminergic (DA) neurons. Our results showed that Agilent's Whole Human Genome Oligonucleotide Microarray permits the monitoring of at least 41000 genes as cells differentiate. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13497
4 Samples

Download data: TXT

Series

Accession:: GSE25931

ID:: 200025931

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000722677.

Blood transcriptomics of drug-naïve sporadic Parkinson’s disease patients

(Submitter supplied) Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder that is clinically defined in terms of motor symptoms. These are preceded by prodromal non-motor manifestations that prove the systemic nature of the disease. Identifying genes and pathways altered in living patients provide new information on the diagnosis and pathogenesis of sporadic PD. We study changes in gene expression in the blood of 40 sporadic PD patients and 20 healthy controls (“Discovery set”) by taking advantage of the Affymetrix platform. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL571
59 Samples

Download data: CEL

Series

Accession:: GSE72267

ID:: 200072267

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000426088.

Whole-transcriptome high-throughput RNA sequencing of blood leukocytes from Parkinson's disease human patients pre- and post-deep brain stimulation

(Submitter supplied) The given data set is the first deep sequencing transcriptome-wide data set of human Parkinson's disease (PD) patients RNA. The data set was produced from blood leukocytes of PD patients, from the same patients following deep brain stimulation (DBS), and from matched healthy control volunteers. Post-DBS samples were taken from the patients while being on electrical stimulation (ON-Stim), and following one hour off of electrical stimulation (OFF-Stim state). more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL9442
13 Samples

Download data: BED, GFF3, TAB, TXT

Series

Accession:: GSE42608

ID:: 200042608

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000202959.

Transcriptional analysis of multiple brain regions in Parkinson's disease

(Submitter supplied) Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. This SuperSeries is composed of the SubSeries listed below.