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Links from GEO DataSets

Items: 12

1.
Full record GDS2982

CD11b-plus CD11c-minus macrophages of the intestinal lamina propria

Comparison of CD11b+ CD11c- macrophages of the small intestinal lamina propria and the spleen. The intestinal immune system responds robustly to pathogens yet remains tolerant to commensals and food antigens. Results provide insight into the role of intestinal macrophages in immune tolerance.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type sets
Platform:
GPL1261
Series:
GSE8868
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS2982
ID:
2982
2.

Comparison of splenic and small intestine lamina propria macrophages

(Submitter supplied) The intestinal immune system must elicit robust immunity against harmful pathogens but restrain immune responses directed against commensal microbes and dietary antigens. The mechanisms that maintain this dichotomy are poorly understood. Here we describe a population of CD11b+F4/80+CD11c– macrophages in the lamina propria (LP) that express several anti-inflammatory molecules including interleukin 10 (IL-10), but little or no pro-inflammatory cytokines, even upon stimulation with Toll-like receptor (TLR) ligands. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2982
Platform:
GPL1261
4 Samples
Download data: CEL, CHP
Series
Accession:
GSE8868
ID:
200008868
3.

Gene expression induced by flagellin stimulation in IECs and CD11c+ LPCs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
8 Samples
Download data
Series
Accession:
GSE5119
ID:
200005119
4.

Gene expression induced by flagellin stimulation in CD11c+ LPCs

(Submitter supplied) Microarray analysis of IECs from Tlr5+/+ and Tlr5-/- mice stimulated with either medium alone or flagellin (1 µg/ml); to elucidate TLR5-mediated immune responses in CD11c+ LPCs Keywords: ordered
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2212
Platform:
GPL1261
4 Samples
Download data
Series
Accession:
GSE5113
ID:
200005113
5.

Gene expression induced by flagellin stimulation in IECs

(Submitter supplied) Microarray analysis of IECs from Tlr5+/+ and Tlr5–/– mice stimulated with either medium alone or flagellin (1 µg/ml); to elucidate TLR5-mediated immune responses in IECs. Keywords: ordered
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2211
Platform:
GPL1261
4 Samples
Download data
Series
Accession:
GSE5112
ID:
200005112
6.
Full record GDS2212

Flagellin effect on toll-like receptor 5 deficient intestinal lamina propria cells

Analysis of CD11c positive intestinal lamina propria cells (LPC) from toll-like receptor 5 (TLR5) null animals stimulated with flagellin. TLR5 mediates the immune response to flagellin. Results provide insight into the role of CD11c positive LPCs in the innate immune response mediated by TLR5.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE5113
4 Samples
Download data
DataSet
Accession:
GDS2212
ID:
2212
7.
Full record GDS2211

Flagellin effect on toll-like receptor 5 deficient intestinal epithelial cells

Analysis of intestinal epithelial cells (IECs) from toll-like receptor 5 (TLR5) null animals stimulated with flagellin. TLR5 mediates the immune response to flagellin. Results provide insight into the role of IECs in the innate immune response mediated by TLR5.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE5112
4 Samples
Download data
DataSet
Accession:
GDS2211
ID:
2211
8.

TLE3 CUT&Tag-Seq to characterize TLE3-binding sites in colonic macrophages

(Submitter supplied) We found that TLE3 in colonic macrophages mainly occupied distal intergenic regions (48%) and gene body regions (47%) with limited occupancy at the gene proximal regions (5%).
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
1 Sample
Download data: BED
Series
Accession:
GSE200645
ID:
200200645
9.

H3K27Ac CUT&Tag-Seq to characterize the epigenetic profiles in colonic macrophages from Tle4KO (Tle4fl/fl, Lyz2-Cre) and WT (Lyz2-Cre) mice

(Submitter supplied) We found that TLE4 maintained epigenetic landscape in colonic macrophages.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
2 Samples
Download data: BED
Series
Accession:
GSE200643
ID:
200200643
10.

TLE3 and TLE4-coordinated colonic macrophage-CD4+ T cell crosstalk maintains intestinal immune homeostasis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
5 Samples
Download data: TXT
Series
Accession:
GSE183236
ID:
200183236
11.

ATAC-Seq to profile the chromatin accessibility in colonic macrophages from Tle4KO (Tle4fl/fl, Lyz2-Cre) and WT (Lyz2-Cre) mice

(Submitter supplied) We found that TLE4 maintained overall chromatin accessibility in colonic macrophages.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
2 Samples
Download data: TXT
Series
Accession:
GSE183235
ID:
200183235
12.

RNA-Seq to profile transcriptomes in colonic macrophages from Tle3KO (Tle3fl/fl, Lyz2-Cre), Tle4KO (Tle4fl/fl, Lyz2-Cre) and WT (Lyz2-Cre) mice

(Submitter supplied) We identified TLE3- and TLE4-regulated transcriptomes in colonic macrophages.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
3 Samples
Download data: TXT
Series
Accession:
GSE183232
ID:
200183232
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Supplemental Content

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