Similar studies for GEO DataSets (Select 200224309) - GEO DataSets

Select item 2002243091.

Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer

(Submitter supplied) Bladder cancer is one of the most common cancer types worldwide and is characterized by a high rate of recurrence. Previous studies have demonstrated that plasminogen activator inhibi-tor-1 (PAI1) plays an important role in bladder cancer development. The aim of our retrospective study was to assess the effects of PAI1 mutational status in bladder tumors. In this study, we evaluated the mutational status of PAI1 in a series of independent cohorts, comprised of a total of 660 subjects. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
16 Samples

Download data: XLSX

Series

Accession:: GSE224309

ID:: 200224309

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001258022.

Plasminogen activator inhibitor 1 (PAI1) promotes actin cytoskeleton reorganization and glycolytic metabolism in triple negative breast cancer

(Submitter supplied) We altered the expression of PAI1 in SUM159 breast cancer cell line and would like to see the effects

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
2 Samples

Download data: DIFF

Series

Accession:: GSE125802

ID:: 200125802

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2002015183.

PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL24676 GPL16791
14 Samples

Download data: BED, BEDGRAPH

Series

Accession:: GSE201518

ID:: 200201518

PubMed Full text in PMC Similar studies

Select item 2002015174.

PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity [RNA-Seq]

(Submitter supplied) The extracellular activity of Plasminogen activator inhibitor-1 (PAI-1) is well described, acting as an inhibitor of tissue plasminogen activator and urokinase-type plasminogen activator, impacting fibrinolysis. Recent studies have revealed a pro-tumorigenic role of PAI-1 in human cancers, via the regulation of angiogenesis and tumor cell survival. In this study, immunohistochemical staining of 939 human bladder cancer specimens showed that PAI-1 expression levels correlated with tumor grade, tumor stage and overall survival. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
8 Samples

Download data: CSV

Series

Accession:: GSE201517

ID:: 200201517

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2002015155.

PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity [ChIP-Seq]

(Submitter supplied) The extracellular activity of Plasminogen activator inhibitor-1 (PAI-1) is well described, acting as an inhibitor of tissue plasminogen activator and urokinase-type plasminogen activator, impacting fibrinolysis. Recent studies have revealed a pro-tumorigenic role of PAI-1 in human cancers, via the regulation of angiogenesis and tumor cell survival. In this study, immunohistochemical staining of 939 human bladder cancer specimens showed that PAI-1 expression levels correlated with tumor grade, tumor stage and overall survival. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL16791
6 Samples

Download data: BED, BEDGRAPH

Series

Accession:: GSE201515

ID:: 200201515

PubMed Full text in PMC Similar studies

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