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Links from GEO DataSets

Items: 15

1.

The involvement of CdhR in Porphyromonas gingivalis during Nitric Oxide stress [RNA-seq]

(Submitter supplied) To understand the role of CdhR and its adjacent gene PG1236 in nitric oxide (NO) stress resistance, isogenic mutants P. gingivalis FLL457 (ΔPG1237::ermF), FLL458 (ΔPG1236::ermF) and FLL459 (ΔPG1236-37::ermF) were made by allelic exchange mutagenesis and their gene expression was studied under control and NO stress conditions. DNA microarray analysis of FLL457 showed that approximately 2% of the genes were up regulated and over 1% of the genes down regulated. more...
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33075
12 Samples
Download data: XLSX
Series
Accession:
GSE224065
ID:
200224065
2.

The involvement of CdhR in Porphyromonas gingivalis during Nitric Oxide stress

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Haemophilus influenzae; Porphyromonas gingivalis W83; Porphyromonas gingivalis
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL33075 GPL18755
24 Samples
Download data
Series
Accession:
GSE224067
ID:
200224067
3.

The involvement of CdhR in Porphyromonas gingivalis during Nitric Oxide stress [microarray]

(Submitter supplied) To understand the role of CdhR and its adjacent gene PG1236 in nitric oxide (NO) stress resistance, isogenic mutants P. gingivalis FLL457 (ΔPG1237::ermF), FLL458 (ΔPG1236::ermF) and FLL459 (ΔPG1236-37::ermF) were made by allelic exchange mutagenesis and their gene expression was studied under control and NO stress conditions. DNA microarray analysis of FLL457 showed that approximately 2% of the genes were up regulated and over 1% of the genes down regulated. more...
Organism:
Porphyromonas gingivalis W83; Haemophilus influenzae
Type:
Expression profiling by array
Platform:
GPL18755
12 Samples
Download data: XLS
Series
Accession:
GSE224064
ID:
200224064
4.

Role of an extracytoplasmic function sigma factor, PGN_0319, in hemin utilization by Porphyromonas gingivalis

(Submitter supplied) Extracytoplasmic function (ECF) sigma factors are known to play an important role in the bacterial response to various environmental stresses. Porphyromonas gingivalis, a prominent etiological agent in human periodontitis, possesses six putative ECF sigma factors. So far, information is limited on an ECF sigma factor, PGN_0319. It has been recently reported that the expression of genes encoding some of the ECF sigma factors including PGN_0319 was affected by hemin availability. more...
Organism:
Porphyromonas gingivalis; Porphyromonas gingivalis ATCC 33277
Type:
Expression profiling by array
Platform:
GPL21477
4 Samples
Download data: TXT
Series
Accession:
GSE78048
ID:
200078048
5.

Transcriptome analysis of PG0686 mutant in co-culture with Porphyromonas gingivalis II

(Submitter supplied) We use high through put RNA sequenceing technology to study the genome-wide expression profile of a unknown-function gene PG0686 mutant, designated as FLL361, in key-stone oral pathogen Porphyromonas gingivalis under anaerobic conditions and oxidative stress conditions.
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32620
12 Samples
Download data: CSV
Series
Accession:
GSE212414
ID:
200212414
6.

Response of Porphyromonas gingivalis to nitrosative stress

(Submitter supplied) Transcriptional profiling of P. gingivalis cells comparing cells grown in anaerobic conditions to cells grown in anaerobic conditions and exposed to nitrite and to GSNO.
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by array
Platform:
GPL15605
2 Samples
Download data: GPR
Series
Accession:
GSE38220
ID:
200038220
7.

Hemin and Iron transcriptome of Porphyromonas gingivalis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by array
Platform:
GPL15605
9 Samples
Download data: CSV
Series
Accession:
GSE50703
ID:
200050703
8.

Hemin and Iron transcriptome of Porphyromonas gingivalis (part 2)

(Submitter supplied) Transcriptional profiling of P. gingivalis cells comparing cells grown under iron replete conditions to that grown under iron depleted conditions
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by array
Platform:
GPL15605
6 Samples
Download data: CSV
Series
Accession:
GSE50702
ID:
200050702
9.

Hemin and iron transcriptome of Porphyromonas gingivalis (part 1)

(Submitter supplied) Transcriptional profiling of P. gingivalis cells comparing cells grown under hemin replete conditions to that grown under hemin depleted conditions
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by array
Platform:
GPL15605
3 Samples
Download data: CSV
Series
Accession:
GSE50701
ID:
200050701
10.

The distinct immune-stimulatory capacities of Porphyromonas gingivalis strains 381 and 33277 are determined by the fimB allele and gingipain activity

(Submitter supplied) The genomes of P. gingivalis strains 33277 and 381 are highly related phylogenetically. However, 33277 displays a reduced capacity to stimulate HEK cell TLR2-dependent signaling and THP-1 cell-dependent IL-1β production compared to 381, suggesting strain-specific differences in the expression of one or more bacterial immune-modulatory cell surface molecules. Genomic sequencing identified a single nucleotide polymorphism in the 33277 fimB allele (A>T), encoding a truncated FimB protein, relative to the 381 fimB allele. more...
Organism:
Porphyromonas gingivalis ATCC 33277; Porphyromonas gingivalis 381
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL26349 GPL25781
6 Samples
Download data: XLSX
Series
Accession:
GSE128899
ID:
200128899
11.

Porphyromonas gingivalis 33277 wild-type vs Fur orthologue Har isogenic mutant ECR455

(Submitter supplied) Porphyromonas gingivalis is a major pathogen associated with the microbial biofilm-mediated disease chronic periodontitis. P. gingivalis has an obligate requirement for iron and protoporphyrin IX which it satisfies by transporting heme and iron liberated from the human host. The level of cellular iron in P. gingivalis affects the expression of a distinct iron-associated regulon of 64 genes and low iron invokes an iron sparing response. more...
Organism:
Porphyromonas gingivalis W83; Porphyromonas gingivalis ATCC 33277
Type:
Expression profiling by array
Platform:
GPL1438
6 Samples
Download data: GPR
Series
Accession:
GSE37099
ID:
200037099
12.

Transcriptome analysis of Filifactor alocis in co-culture with Porphyromonas gingivalis

(Submitter supplied) We use high through put RNA sequenceing technology to study the genome-wide expression profile in an oral pathogen Filifactor alocis when co-cultured with another key-stone oral pathogen Porphyromonas gingivalis under anaerobic conditions and oxidative stress conditions.
Organism:
Filifactor alocis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30499
6 Samples
Download data: CSV
Series
Accession:
GSE181879
ID:
200181879
13.

Aerobic transcriptome of Porphyromonas gingivalis

(Submitter supplied) Transcriptional profiling of P. gingivalis cells comparing control cells grown in anaerobic conditions with cells grown in the presence of 6% of oxygen
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by array
Platform:
GPL9149
5 Samples
Download data: GPR
Series
Accession:
GSE17960
ID:
200017960
14.

Role of HcpR in nitrosative stress protection

(Submitter supplied) HcpR has been shown to be required for growth of Porphyromonas gingivalis in the presence of nitrite (Infect Immun. 2012 Sep;80(9):3319-31. doi: 10.1128/IAI.00561-12. Epub 2012 Jul 9). It also has been shown to regulate the expression of hcp. To define the entire regulon of HcpR RNAseq examination of the wild type and mutant (deficient in HcpR) strains have been used to define the regulon in response to nitrite exposure in bacteria grown in the presence and absence of nitrite. more...
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25359
16 Samples
Download data: XLS
Series
Accession:
GSE117421
ID:
200117421
15.

Identification of bistable populations of Porphyromonas gingivalis that differ in epithelial cell invasion.

(Submitter supplied) Bistable populations of bacteria give rise to two or more subtypes that exhibit different phenotypes. We have explored whether the periodontal pathogen, Porphyromonas gingivalis, exhibits bistable invasive phenotypes. Using a modified cell invasion assay, we show for the first time that there are two distinct sub-types within a population of P.ginigivalis strains NCTC 11834 and W50 that display differences in their ability to invade oral epithelial cells. more...
Organism:
Porphyromonas gingivalis
Type:
Expression profiling by array
Platform:
GPL10575
24 Samples
Download data: MEV
Series
Accession:
GSE23021
ID:
200023021
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