GEO DataSets

(Submitter supplied) Acetate is a simple carboxylic acid that is synthesized in various microorganisms. Although acetate toxicity and tolerance have been studied in many microorganisms, little is known about the effects of exogenous acetate on the cell growth of acetogenic bacteria. In this study, we report the phenotypic changes that occurred in the acetogenic bacterium Clostridium sp. AWRP as a result of an adaptive laboratory evolution under acetate challenge. more...

Organism:

Clostridium sp. AWRP

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32381

8 Samples

Download data: XLSX

(Submitter supplied) Acetogenic bacteria utilize cellular redox energy to convert CO2 to acetate using the Wood-Ljungdahl (WL) pathway. Such redox energy can be derived from electrons generated from H2 as well as inorganic materials such as photo-responsive semiconductors. To reveal how acetogenic bacteria utilize electrons generated from external energy sources to reduce CO2, we developed a nanoparticle-microbe hybrid system and generated RNA-seq results.

Organism:

Clostridium autoethanogenum DSM 10061

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29115

9 Samples

Download data: TXT

(Submitter supplied) Autotrophic conversion of CO2 to value-added biochemicals has received considerable attention for the sustainable route to replace the fossil fuels. Particularly, anaerobic acetogenic bacteria are naturally capable of reducing CO2 or CO to various metabolites. To fully utilize their biosynthetic potential, systemic understanding of the metabolic network with the transcriptional and translational regulation of the corresponding genes is highly demanded. more...

Organism:

Eubacterium limosum

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL23275 GPL23276

10 Samples

Download data: FA, GFF, TXT

(Submitter supplied) Expression profile of wild-type S. ovata and methanol-adapted strain grown autotrophically with H2 as the source of electron.

Organism:

Sporomusa ovata DSM 2662

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19818

6 Samples

Download data: TXT

(Submitter supplied) The Wood-Ljungdahl pathway in acetogens converts C1 compounds, such as CO2 and CO, into acetyl-CoA. Similarly, the glycine synthase pathway assimilates C1 compounds into glycine. Partial glycine synthase genes are widely conserved in the Wood-Ljungdahl pathway gene cluster but functional relationship between the pathways in autotrophic condition remains unknown. To comprehend, we assembled Clostridium drakei genome (5.7-Mbp) with intact glycine synthase pathway and constructed a genome-scale metabolic model, iSL836, predicting increased metabolic flux rates of the Wood-Ljungdahl pathway and the glycine synthase-reductase associated reactions under autotrophic conditions. more...

Organism:

Clostridium drakei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25449

4 Samples

Download data: TXT