GEO DataSets

(Submitter supplied) Gene expression profile (GEP) was analyzed in DLBCL cases to compare early failure patients (10) vs. responding patients (29), to identify features associated to primary chemoresistance

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL13667

39 Samples

Download data: CEL

(Submitter supplied) We studied 498 de-novo adult DLBCL cases, which had been diagnosed between January 2002 and October 2009, as part of the International DLBCL Rituximab-CHOP Consortium Program Study We perform global gene expression profiling from formalin fixed paraffin embedded 498 DLBCL tissues RNA by SPIA mediated microarray detection and identified the distinct subgroups of the disease within DLBCL, known as germinal-center-B-cell-like (GCB), activated B-cell-like (ABC), and unclassified DLBCL (UC).

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

498 Samples

Download data: CEL, PDF

(Submitter supplied) We used microarray data sets to determine concordance of microarray vs qRT-PCR based LCOO cell-of-origin for Diffuse large B-cell Lymphome subtypes.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

180 Samples

Download data: CEL

(Submitter supplied) We studied the DNA methylation profiles of 93 LBCL cases: Diffuse large B-cell lymphoma not otherwise specified (DLBCL, n=66), High-grade B-cell lymphoma (n=7), Primary CNS lymphoma (n=8), and transformation of indolent B-cell lymphoma (n=12). One sample of normal GC B-cells from tonsils was included as a control. LBCL cases had a particularly aberrant semimethylated pattern with large intertumor variation and overall low hypermethylation. more...

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL23976

97 Samples

Download data: IDAT, TXT

(Submitter supplied) Fifty-eight retrospectively-ascertained local cases of diffuse large B-cell lymphoma (DLBCL) were segregated into two large subgroups with divergent overall survival through expression profiling of 135 transcripts including 92 regulated downstream of TCF3 or recurrently mutated in DLBCL or Burkitt lymphoma

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL32602

58 Samples

Download data: RCC

(Submitter supplied) The transcriptomic profiles of two resistant (HT and OCI-LY3) and two sensitive (SUDHL5 and OCI-LY19) DLBCL cell lines before and after doxorubicin treatment were analysed by RNA-seq. To further investigate the molecular basis underlying the development of doxorubicin resistance, acquired doxorubicin-resistant cells (OCI-LY19R) were generated by periodically treating the parental doxorubicin-sensitive OCI-LY19 cells (OCI-LY19S) with increasing doses of doxorubicin over a prolonged period till its IC50 exceeded 200 nM. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20795

30 Samples

Download data: TXT

(Submitter supplied) Gene expression profiling was carried out for RNA extracted from Formalin-fixed, paraffin embedded (FFPE) biopsies for 1311 patients with diffuse large b-cell lymphoma (DLBCL) using the Illumina DASL platform.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL14951

1310 Samples

Download data: TXT