GEO DataSets

(Submitter supplied) Background and aim: The disease course and clinical phenotype in multiple sclerosis (MS) are highly variable and therefore, biomarkers are needed. Studies have shown a dysregulation in the coding and non-coding RNAs and proposed some as biomarkers. However, still none of them have reached the clinical practice. Recently, circular RNAs (circRNAs) have emerged as new players in the transcriptome that hold a great potential as biomarkers in several diseases. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20795

50 Samples

Download data: CSV

(Submitter supplied) The aim was to investigate the total circular RNA profile in patients with relapsing–remitting multiple sclerosis and healthy control. We analyzed close to 14,000 individual circRNA per sample.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL21825

30 Samples

Download data: TXT

(Submitter supplied) The circRNA profiles of 24 CAD patients and 7 controls were performed by microarray. Six classifiers were used to evaluate potential circRNAs biomarkers. The expression levels of candidate circRNAs were further verified by qRT-PCR in large cohorts. Logistic regression analysis and receiver operating characteristic were conducted to assess the diagnostic value. A total of 624 circRNAs and 171 circRNAs were significantly upregulated and downregulated, respectively, in CAD patients relative to controls. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL22121

31 Samples

Download data: TXT

(Submitter supplied) Circular RNAs (circRNAs) are a new class of endogenous and regulatory non-coding RNAs, but their expressions in tumor and plasma are largely unknown. Here, our study firstly suggested that microarray should be more efficient than RNA sequencing for circRNA profiling. Then, we detected ~80,000 circRNAs expressed in cervical tumors and matched normal tissues by microarray, and ~23,000 of them are differently expressed. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL16791

10 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array; Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:

GPL20115 GPL22722 GPL16791

55 Samples

Download data: TXT

(Submitter supplied) Circular RNAs (circRNAs) are a new class of endogenous and regulatory non-coding RNAs, but their expressions in tumor and plasma are largely unknown. Here, our study firstly suggested that microarray should be more efficient than RNA sequencing for circRNA profiling. Then, we detected ~80,000 circRNAs expressed in cervical tumors and matched normal tissues by microarray, and ~23,000 of them are differently expressed. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL22722

4 Samples

Download data: TXT, XLSX

(Submitter supplied) Circular RNAs (circRNAs) are a new class of endogenous and regulatory non-coding RNAs, but their expressions in tumor and plasma are largely unknown. Here, our study firstly suggested that microarray should be more efficient than RNA sequencing for circRNA profiling. Then, we detected ~80,000 circRNAs expressed in cervical tumors and matched normal tissues by microarray, and ~23,000 of them are differently expressed. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL22722

21 Samples

Download data: TXT, XLSX

(Submitter supplied) Circular RNAs (circRNAs) are a new class of endogenous and regulatory non-coding RNAs, but their expressions in tumor and plasma are largely unknown. Here, our study firstly suggested that microarray should be more efficient than RNA sequencing for circRNA profiling. Then, we detected ~80,000 circRNAs expressed in cervical tumors and matched normal tissues by microarray, and ~23,000 of them are differently expressed. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL20115

10 Samples

Download data: TXT, XLSX

(Submitter supplied) Circular RNAs (circRNAs) are a new class of endogenous and regulatory non-coding RNAs, but their expressions in tumor and plasma are largely unknown. Here, our study firstly suggested that microarray should be more efficient than RNA sequencing for circRNA profiling. Then, we detected ~80,000 circRNAs expressed in cervical tumors and matched normal tissues by microarray, and ~23,000 of them are differently expressed. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL22722

10 Samples

Download data: TXT, XLSX

(Submitter supplied) The aim of this study was to analyze the expression profile of circRNAs in PBMCs in peripheral blood of patients with hepatocellular carcinoma (HCC) by next-generation sequencing, and to identify potential markers for early diagnosis and prognosis of HCC, and to lay a foundation for further study on the mechanism of this molecule in PBMCs.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20795

7 Samples

Download data: TXT

(Submitter supplied) We have employed circRNA microarray expression profiling as a discovery platform to identify the dysregulated circRNAs in human abdominal aortic aneurysm.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL21825

8 Samples

Download data: TXT

(Submitter supplied) A comprehensive profiling of known human circular RNA is performed on both TB patient and healthy control.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23259

4 Samples

Download data: CSV, XLSX

(Submitter supplied) Hepatic echinococcosis (HE) caused by Echinococcus spp. transmitted from carnivores is known as a severe zoonotic disease that formed into hepatic cystic echinococcosis (HCE) and hepatic alveolar echinococcosis (HAE). It continues to be a serious public health issue around the world. HAE is uncommon infection which is characterized by poor prognosis but it is the most life-threatening compare to HCE. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20301

6 Samples

Download data: XLSX

(Submitter supplied) We performed microarray analysis to determine the expression profiles of miRNAs during osteoblast differentiation of BMSCs

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL25134

4 Samples

Download data: TXT

(Submitter supplied) We performed microarray analysis to determine the expression profiles of circRNAs during osteoblast differentiation of BMSCs

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23467

4 Samples

Download data: TXT

(Submitter supplied) Cellular circular RNAs (circRNAs) are generated by head-to-tail splicing and are present in all multicellular organisms studied so far. Recently, circRNAs have emerged as large class of RNA which can function as post-transcriptional regulators. It has also been shown that many circRNAs are tissue- and stage specifically expressed. Moreover, the unusual stability and expression specificity make circRNAs important candidates for clinical biomarker research. more...

Organism:

Homo sapiens

Type:

Other

Platform:

GPL11154

24 Samples

Download data: TXT

(Submitter supplied) To explore the differentially expressed (DE) circular (circ)RNAs, competing endogenous RNAs networks, and potential biomarkers in distal cholangiocarcinoma (dCCA), using microarray analysis, a comprehensive circRNA expression profiling was constructed with six paired dCCA tumor and adjacent normal samples. A total of 171 DE circRNAs were identified. Three upregulated (hsa_circ_0060144, hsa_circ_0008274, and hsa_circ_0000673) and two downregulated circRNAs (hsa_circ_0139402 and hsa_circ_0001714) were validated with RT-qPCR in 40 dCCA patients. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL21825

12 Samples

Download data: TXT, XLS

(Submitter supplied) CircRNA microarray was conducted to further explore the underlying circRNA expression alterations in extramedullary infiltration (EMI) of AML. 4 matched samples from EMI, non-EMI AML patients and healthy volunteers were selected. Mononuclear cells from 12 bone marrow samples were separated according to protocols. RNA was then extracted and hybridization for further microarray analysis.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL21825

12 Samples

Download data: TXT

(Submitter supplied) Whole Genome microarray was conducted to further explore the underlying gene expression alterations in extramedullary infiltration (EMI) of AML. 4 matched samples from EMI, non-EMI AML patients and healthy volunteers were selected. Mononuclear cells from 12 bone marrow samples were separated according to protocols. RNA was then extracted and hybridization for further microarray analysis.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL13497

12 Samples

Download data: TXT

(Submitter supplied) Circular RNAs (circRNA) are special non-coding RNAs. They are widely present, but with unknown functions. Recent studies have shown that many endogenous circRNAs have sponge function to absorb microRNAs. They can regulate target gene mRNA expression and play important roles in many biological processes. However, expression profile and function of circRNAs in human TSCC haven’t been reported. High-throughput sequencing was performed to identify and annotate from three TSCC tissues and adjacent tissues. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20301

6 Samples

Download data: XLS