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Links from GEO DataSets

Items: 20

1.

Dynamic placement of the linker histone H1 regulates nucleosome arrangement and coordinates gene transcription in early Drosophila embryos[ChIP-Seq]

(Submitter supplied) H1 ChIP-seq profiling and nucleosome MNase-seq profiling were performed in after egg laying (AEL) 3-4 hours (hr) and 14-15hr Drosophila melanogaster embryos (W1118).
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13304
6 Samples
Download data: TAB, TDF
Series
Accession:
GSE101327
ID:
200101327
2.

Dynamic placement of the linker histone H1 regulates nucleosome arrangement and coordinates gene transcription in early Drosophila embryos

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL13304
7 Samples
Download data: FPKM_TRACKING, TAB, TDF
Series
Accession:
GSE101330
ID:
200101330
3.

Dynamic placement of the linker histone H1 regulates nucleosome arrangement and coordinates gene transcription in early Drosophila embryos[RNA-Seq]

(Submitter supplied) Expression profiles of in after egg laying (AEL) 3-4 hours (hr) and 14-15hr Drosophila melanogaster embryos (W1118)
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
1 Sample
Download data: FPKM_TRACKING
Series
Accession:
GSE101328
ID:
200101328
4.

Genome-wide maps of HMGD1 and H1-bound nucleosomes.

(Submitter supplied) Chromatin architectural proteins interact with nucleosomes to modulate chromatin accessibility and higher-order chromatin structure. While these proteins are almost certainly important for gene regulation they have been studied far less than the core histone proteins. Here we describe the genomic distributions and functional roles of two chromatin architectural proteins: histone H1 and the high mobility group protein HMGD1, in Drosophila S2 cells. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL10942
7 Samples
Download data: WIG
Series
Accession:
GSE49526
ID:
200049526
5.

Nucleosome fragility is associated with future transcriptional response to developmental cues and stress in C. elegans

(Submitter supplied) Nucleosomes have structural and regulatory functions in all eukaryotic DNA-templated processes. The position of nucleosomes on DNA and the stability of the underlying histone-DNA interactions affect the access of regulatory proteins to DNA. Both stability and position are regulated through DNA sequence, histone post-translational modifications, histone variants, chromatin remodelers, and transcription factors. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18245
24 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE79567
ID:
200079567
6.

The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo

(Submitter supplied) We addressed the roles of three nucleosome spacing enzymes (ISW1, ISW2 and CHD1) in specifying chromatin organization in S. cerevisiae.
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13821
36 Samples
Download data: BEDGRAPH
Series
Accession:
GSE69400
ID:
200069400
7.

Genomic analysis of N. crassa histone H1

(Submitter supplied) Histone H1 variants, known as linker histones, are essential chromatin components in higher eukaryotes, yet compared to the core histones relatively little is known about their in vivo functions. The filamentous fungus Neurospora crassa encodes a single H1 protein that is not essential for viability. To investigate the role of N. crassa H1, we constructed a functional FLAG-tagged H1 fusion protein and performed genomic and molecular analyses. more...
Organism:
Neurospora crassa
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL20705 GPL20660
22 Samples
Download data: TDF, TXT
Series
Accession:
GSE78157
ID:
200078157
8.

Histone H1 limits DNA methylation in Neurospora

(Submitter supplied) Analysis of DNA methylation in wildtype and mutants lacking histone H1 revealed increased DNA methylation when H1 is absent.
Organism:
Neurospora crassa
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL20660
7 Samples
Download data: TSV, TXT
Series
Accession:
GSE76982
ID:
200076982
9.

Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13304
14 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE80458
ID:
200080458
10.

Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos [ChIP-seq]

(Submitter supplied) Chromatin profiling of affinity-purified nuclei of neural stem cells (NSCs) and neurons from the Drosophila embryos, respectively.
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13304
12 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE80457
ID:
200080457
11.

Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos [RNA-seq]

(Submitter supplied) Expression profiles of affinity-purified nuclei of neural stem cells (NSCs) and neurons from the Drosophila embryos.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
2 Samples
Download data: TXT
Series
Accession:
GSE80456
ID:
200080456
12.

Novel nucleosomal particles containing core histones and linker DNA but no histone H1

(Submitter supplied) Eukaryotic chromosomal DNA is assembled into regularly spaced nucleosomes, which play a central role in gene regulation by determining accessibility of control regions. The nucleosome contains ~147 bp of DNA wrapped ~1.7 times around a central core histone octamer. The linker histone, H1, binds both to the nucleosome, sealing the DNA coils, and to the linker DNA between nucleosomes, directing chromatin folding. more...
Organism:
Mus musculus; Synthetic plasmid; Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
31 Samples
Download data: BW, FA, TXT
Series
Accession:
GSE65889
ID:
200065889
13.

Isw2 ChIP in S cerevisiae

(Submitter supplied) Study to detect to genome wide localization of the ATP dependent chromatin remodelling factor Isw2 using ChIP. Keywords: ChIP chip
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL6476
6 Samples
Download data: CEL
Series
Accession:
GSE8815
ID:
200008815
14.

Mapping Nucleosome positions in WT and delta isw2 cells

(Submitter supplied) To map nucleosome positions in WT and delta isw2 cells Keywords: Nucleosomal DNA hybridization
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL6476
8 Samples
Download data: CEL
Series
Accession:
GSE8814
ID:
200008814
15.

Mapping chromatin remodelling in delta isw2 cells

(Submitter supplied) To define chromatin structure changes along the yeast genome using microarrays. Nucleosomal DNA from WT and delta isw2 yeast were hybridized and differences in signals were calculated. Keywords: Nucleosomal DNA hybridization
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL6476
4 Samples
Download data: CEL
Series
Accession:
GSE8813
ID:
200008813
16.

Genome-wide chromatin reconstitution with Drosophila embryo extract and nucleosome positioning by CG7372 and su(Hw)

(Submitter supplied) We have reconstituted chromatin in vitro on a genome-wide level by incubating total genomic Drosophila melanogaster DNA in D. melanogaster preblastoderm embryo extract. We analyzed chromatin reconstituted with 1) extract from wildtype embryos, 2) extract from embryos lacking the chromatin remodeling enzyme subunit Acf , and 3) extract from Acf-mutant embryos supplemented with recombinant ACF (Acf + Iswi). more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19951
10 Samples
Download data: BEDGRAPH
Series
Accession:
GSE118335
ID:
200118335
17.

ACF1 regulates nucleosome spacing in Drosophila euchromatin

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19951
20 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE85407
ID:
200085407
18.

ACF1 regulates nucleosome spacing in Drosophila euchromatin [MNase-seq BG3]

(Submitter supplied) The nature of chromatin as regular succession of nucleosomes has gained iconic status. The average nucleosome repeat length (NRL) determined by classical means serves as index for bulk chromatin of a given specimen. However, this value is dominated by regular heterochromatin since nucleosomal arrays are often not regular at individual single copy sequences. To obtain a measure for nucleosome regularity in euchromatin we subjected nucleosome dyad profiles to autocorrelation and spectral density analyses. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19951
8 Samples
Download data: BEDGRAPH
Series
Accession:
GSE85406
ID:
200085406
19.

ACF1 regulates nucleosome spacing in Drosophila euchromatin [Mnase-seq embryos]

(Submitter supplied) The nature of chromatin as regular succession of nucleosomes has gained iconic status. The average nucleosome repeat length (NRL) determined by classical means serves as index for bulk chromatin of a given specimen. However, this value is dominated by regular heterochromatin since nucleosomal arrays are often not regular at individual single copy sequences. To obtain a measure for nucleosome regularity in euchromatin we subjected nucleosome dyad profiles to autocorrelation and spectral density analyses. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19951
8 Samples
Download data: BEDGRAPH
Series
Accession:
GSE85405
ID:
200085405
20.

ACF1 regulates nucleosome spacing in Drosophila euchromatin [ChIP-seq]

(Submitter supplied) The nature of chromatin as regular succession of nucleosomes has gained iconic status. The average nucleosome repeat length (NRL) determined by classical means serves as index for bulk chromatin of a given specimen. However, this value is dominated by regular heterochromatin since nucleosomal arrays are often not regular at individual single copy sequences. To obtain a measure for nucleosome regularity in euchromatin we subjected nucleosome dyad profiles to autocorrelation and spectral density analyses. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19951
4 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE85404
ID:
200085404
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