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Links from GEO DataSets

Items: 4

1.

Gene expression changes induced by overexpression of EVI1 in Lin- hematopoietic cells [EVI1_ST]

(Submitter supplied) The transcription factor Evi1 is essential for the formation and maintenance of hematopoietic stem cells, and induces clonal dominance with malignant progression upon constitutive activation by chromosomal rearrangements or transgene integration events. To understand the immediate and adaptive response of primary murine hematopoietic cells to the transcriptional upregulation of Evi1, we developed an inducible lentiviral vector system with a robust expression switch. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
6 Samples
Download data: CEL
Series
Accession:
GSE39103
ID:
200039103
2.

Gene expression changes induced by overexpression of EVI1 in Lin- hematopoietic cells [Lin]

(Submitter supplied) The transcription factor Evi1 is essential for the formation and maintenance of hematopoietic stem cells, and induces clonal dominance with malignant progression upon constitutive activation by chromosomal rearrangements or transgene integration events. To understand the immediate and adaptive response of primary murine hematopoietic cells to the transcriptional upregulation of Evi1, we developed an inducible lentiviral vector system with a robust expression switch. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
6 Samples
Download data: CEL
Series
Accession:
GSE34729
ID:
200034729
3.

The expression profiles of AML cell lines

(Submitter supplied) EVI1 is one of the famous poor prognostic markers for a chemotherapy-resistant acute myeloid leukemia (AML). To identify molecular targets on the surface of leukemia cells with EVI1high expression, we compared the gene expression profiles of several AML cell lines by DNA microarray
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4497
Platform:
GPL570
12 Samples
Download data: CEL
Series
Accession:
GSE35159
ID:
200035159
4.
Full record GDS4497

Acute myeloid leukemia cell lines with high Ecotropic Viral Integration site 1 expression

Analysis of acute myeloid leukemia (AML) cell lines with high or low Ecotropic viral integration site 1 (EVI1) expression. High EVI1 levels predict adverse outcome in chemotherapy-resistant AML patients. Results provide insight into novel molecular targets in AML with high EVI1 expression.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 12 cell line, 3 disease state, 2 genotype/variation sets
Platform:
GPL570
Series:
GSE35159
12 Samples
Download data: CEL
DataSet
Accession:
GDS4497
ID:
4497
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