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Links from GEO DataSets

Items: 20

1.

DeepCAGE and DeepSAGE with proliferating and differentiated C2C12 mouse myoblasts

(Submitter supplied) We use tag-based next generation sequencing analysis to quantify gene expression levels during myogenic differentiation and focused on the identifcation of novel 3' ends with DeepSAGE and novel 5' ends with DeepCAGE.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9250
14 Samples
Download data: WIG
Series
Accession:
GSE21580
ID:
200021580
2.

Unamplified Cap Analysis of Gene Expression on a single molecule sequencer (HeliScopeCAGE)

(Submitter supplied) We report the development of a simplified Cap Analysis of Gene Expression (CAGE) protocol adapted for single molecule sequencers which avoids second strand synthesis, ligation, digestion and PCR. HeliScopeCAGE directly sequences the 3’ end of cap trapped first strand cDNAs. As with previous versions of CAGE, we better define transcription start sites (TSS) than known models, identify novel regions of transcription and alternative promoters, and find two major classes of TSS signal, sharp peaks and broad regions. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL6884 GPL14761
19 Samples
Download data: TXT
3.

Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis

(Submitter supplied) Skeletal muscle contains long multinucleated and contractile structures known as muscle fibers, which arise from the fusion of myoblasts into nucleated myotubes during myogenesis. The myogenic regulatory factor (MRF) MYF5 is the earliest to be expressed during myogenesis and functions as a transcription factor in muscle progenitor cells (satellite cells) and myocytes. In mouse C2C12 myocytes, MYF5 is implicated in the initial steps of myoblast differentiation into myotubes. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
16 Samples
Download data: TXT
Series
Accession:
GSE73704
ID:
200073704
4.

Expression Profiling of Early Myogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL1261 GPL6105
84 Samples
Download data: CEL
Series
Accession:
GSE17039
ID:
200017039
5.

Expression Profiling of Early Myogenesis - Illumina Dataset

(Submitter supplied) Myogenesis is a tightly controlled process involving the transcriptional activation and repression of thousands of genes. Although many components of the transcriptional network are known for the later phases of myogenesis, relatively little work has described the transcriptional landscape within the first 24 hours, when myoblasts commit to differentiate. Through dense temporal sampling of differentiating C2C12 myoblasts, we identify 266 transcriptional regulators (TRs) whose expression is altered within the first 12 hours of myogenesis. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6105
36 Samples
Download data: TXT
Series
Accession:
GSE17038
ID:
200017038
6.

Expression Profiling of Early Myogenesis - Affymetrix Dataset

(Submitter supplied) Analysis of Early Myogenesis Reveals an Extensive Set of Transcriptional Regulators Whose Knock-down Can Inhibit Differentiation Myogenesis is a tightly controlled process involving the transcriptional activation and repression of thousands of genes. Although many components of the transcriptional network are known for the later phases of myogenesis, relatively little work has described the transcriptional landscape within the first 24 hours, when myoblasts commit to differentiate. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
48 Samples
Download data: CEL
Series
Accession:
GSE16992
ID:
200016992
7.

Gene Expression and Isoform Variation Analysis using Affymetrix Exon Arrays

(Submitter supplied) Background:Alternative splicing and isoform level expression profiling is an emerging field of interest within genomics. Splicing sensitive microarrays, with probes targeted to individual exons or exon-junctions, are becoming increasingly popular as a tool capable of both expression profiling and finer scale isoform detection. Despite their intuitive appeal, relatively little is known about the performance of such tools, particularly in comparison with more traditional 3’ targeted microarrays. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL5175 GPL5188
40 Samples
Download data: CEL
Series
Accession:
GSE13072
ID:
200013072
8.

Gene Expression and Isoform Variation: Exon-level Analysis

(Submitter supplied) Background:Alternative splicing and isoform level expression profiling is an emerging field of interest within genomics. Splicing sensitive microarrays, with probes targeted to individual exons or exon-junctions, are becoming increasingly popular as a tool capable of both expression profiling and finer scale isoform detection. Despite their intuitive appeal, relatively little is known about the performance of such tools, particularly in comparison with more traditional 3’ targeted microarrays. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5188
20 Samples
Download data: CEL
Series
Accession:
GSE13069
ID:
200013069
9.

Gene Expression and Isoform Variation: Gene-level Analysis

(Submitter supplied) Background:Alternative splicing and isoform level expression profiling is an emerging field of interest within genomics. Splicing sensitive microarrays, with probes targeted to individual exons or exon-junctions, are becoming increasingly popular as a tool capable of both expression profiling and finer scale isoform detection. Despite their intuitive appeal, relatively little is known about the performance of such tools, particularly in comparison with more traditional 3’ targeted microarrays. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5175
20 Samples
Download data: CEL
Series
Accession:
GSE13066
ID:
200013066
10.

lncRNA expression in C2C12 myoblasts and myotubes

(Submitter supplied) To determine the lncRNA expression profile in C2C12 myoblasts and myotubes, we used mouse lncRNA microarray from Arraystar to examine the expression of lncRNAs in C2C12 myoblasts and myotubes.
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL19286
6 Samples
Download data: TXT
Series
Accession:
GSE101499
ID:
200101499
11.

Myogenic differentiation_Cchip

(Submitter supplied) In this study, Affymetrix MG_U74Av2 and MG_U74Cv2 GeneChips were used to analyze gene expression over a 12 day time course in C2C12 myoblasts induced to differentiate in vitro. Triplicate cultures were studied during cell proliferation (days -2 and -1), at cell cycle withdrawal (day 0) and during myogenic fusion and maturation of multinucleated myotubes (days 2, 4, 6, 8, 10). The manuscript associated to this work is Tomczak et al., FASEB J., 2003 Dec 19. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS587
Platform:
GPL83
21 Samples
Download data: CEL, EXP, RPT
Series
Accession:
GSE990
ID:
200000990
12.

Myogenic differentiation_Achip

(Submitter supplied) In this study, Affymetrix MG_U74Av2 and MG_U74Cv2 GeneChips were used to analyze gene expression over a 12 day time course in C2C12 myoblasts induced to differentiate in vitro. Triplicate cultures were studied during cell proliferation (days -2 and -1), at cell cycle withdrawal (day 0) and during myogenic fusion and maturation of multinucleated myotubes (days 2, 4, 6, 8, 10). The manuscript associated to this work is Tomczak et al., FASEB J., 2003 Dec 19. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS586
Platform:
GPL81
24 Samples
Download data: CEL, EXP, RPT
Series
Accession:
GSE989
ID:
200000989
13.
Full record GDS587

Myogenic differentiation timecourse (MG-U74C)

Analysis of early stages of myogenesis. C2C12 myoblasts induced to differentiate and examined during cell proliferation (days -2 to -1), at cell cycle withdrawal (day 0) and during myogenic fusion and maturation of multinucleated myotubes (days 2 to 10).
Organism:
Mus musculus
Type:
Expression profiling by array, count, 7 time sets
Platform:
GPL83
Series:
GSE990
21 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS587
ID:
587
14.
Full record GDS586

Myogenic differentiation timecourse (MG-U74A)

Analysis of early stages of myogenesis. C2C12 myoblasts induced to differentiate and examined during cell proliferation (days -2 to -1), at cell cycle withdrawal (day 0) and during myogenic fusion and maturation of multinucleated myotubes (days 2 to 10).
Organism:
Mus musculus
Type:
Expression profiling by array, count, 8 time sets
Platform:
GPL81
Series:
GSE989
24 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS586
ID:
586
15.

Extraocular muscle, expression changes in critical period (Porter lab)

(Submitter supplied) Evaluation of extraocular muscle (EOM) critical period by expression profiling in dark reared rat. Data form part of publication: Investigative Ophthalmology and Visual Sciences 44: 3842-3855, 2003. Keywords: other
Organism:
Rattus norvegicus
Type:
Expression profiling by SAGE
Platform:
GPL23
2 Samples
Download data
Series
Accession:
GSE497
ID:
200000497
16.

SAGE tags generated from Triticum aestivum cultivars Scorpion 25 and Xi19 grown under normal and hot/dry conditions

(Submitter supplied) Triticum aestivum cultivars Scorpion 25 and Xi 19 were grown under both normal and hot/dry conditions. We compared the effect of these two growth conditions on these two closely related varieties.
Organism:
Triticum aestivum
Type:
Expression profiling by SAGE
Platform:
GPL7079
6 Samples
Download data
Series
Accession:
GSE12832
ID:
200012832
17.

miRNA expression profiling in embryonic chicken heart

(Submitter supplied) MicroRNAs are small non-coding RNA transcripts that regulate post-transcriptional gene expression. The millions of short sequence reads generated by next generation sequencing technologies make this technique explicitly suitable for profiling of known and novel microRNAs. A modification to the small-RNA expression kit (SREK, Ambion) library preparation method for the SOLiD sequencing platform is described to generate microRNA sequencing libraries that are compatible with the Illumina Genome Analyzer. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL9385
5 Samples
Download data: WIG
Series
Accession:
GSE20757
ID:
200020757
18.

Wilms tumor versus Stratagene Universal Reference

(Submitter supplied) Gene expression comparison of Wilms tumor RNA versus Stratagene Universal reference RNA Keywords: repeat sample
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1791
Platform:
GPL96
4 Samples
Download data
Series
Accession:
GSE1158
ID:
200001158
19.
Full record GDS1791

Wilms' tumor

Expression profiling of Wilms' tumor tissue after pre-operative chemotherapy. Stratagene Universal Reference RNA also examined. Results are part of a cross-platform evaluation and compared to data generated from Serial Analysis of Gene Expression.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 other sets
Platform:
GPL96
Series:
GSE1158
4 Samples
Download data
20.

Comparative molecular analysis of developing mouse forelimbs and hindlimbs

(Submitter supplied) The analysis of differentially expressed genes is a powerful approach to elucidate the genetic mechanisms underlying the morphological and evolutionary diversity among serially homologous structures, both within the same organism (e.g., hand vs. foot) and between different species (e.g., hand vs. wing). In the developing embryo, limb-specific expression of Pitx1, Tbx4, and Tbx5 regulates the determination of limb identity. more...
Organism:
Mus musculus
Type:
Expression profiling by SAGE
Platform:
GPL11
2 Samples
Download data
Series
Accession:
GSE504
ID:
200000504
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