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Links from GEO DataSets

Items: 20

1.

Allergen induced gene expression of airway epithelial cells shows a possible role for TNF-α

(Submitter supplied) Response to allergen was studied in bronchial epithelial cell line H292. Cells were cultured and subsequently exposed to House dust mite or vessel (saline) Microarray data was analysed using bioinformatics and biostastics. We find a strong response to allergen in epithelial cells Keywords: cellular response to allergen
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3003
Platform:
GPL570
6 Samples
Download data: CEL, EXP
Series
Accession:
GSE9151
ID:
200009151
2.
Full record GDS3003

House dust mite extract effect on a bronchial epithelial cell line

Analysis of H292 bronchial epithelial cells exposed to house dust mite (HDM) extract. More than just a physical barrier, epithelium can produce mediators in response to pathogens and allergens. Results provide insight into the nature of the response of bronchial epithelial cells to HDM allergen.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL570
Series:
GSE9151
6 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3003
ID:
3003
3.

PBECs stimulated with pro-inflammatory cytokines and P. aeruginosa

(Submitter supplied) Comparison of libraries derived from primary human bronchial epithelial cells which are [i] unstimulated, [ii] stimulated with the pro-inflammatory cytokines IL1beta and TNFalpha and [iii] stimulated with heat-inactivated Pseudomonas aeruginosa (strain PAO1). Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
3 Samples
Download data
Series
Accession:
GSE2056
ID:
200002056
4.

Primary nasal epithelium exposed to house dust mite extract shows activated expression in allergics

(Submitter supplied) Response to allergen was studied in epithelial cells derived from allergic pantients and from healthy controls. Cells were cultured after isolation from a nasal biopsy. Cells were exposed to Housed dust mite or vessel (saline) Microarray data was analysed using bioinformatics and biostaistics. We conclude that a marked difference in basal expression and in response to hous dust mite exists Keywords: cellular response to allergen
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3082
Platform:
GPL570
20 Samples
Download data: CEL, EXP
Series
Accession:
GSE9150
ID:
200009150
5.
Full record GDS3082

Allergic nasal epithelium response to house dust mite allergen in vitro

Analysis of cultured nasal epithelia prepared from healthy and allergic individuals following exposure to house dust mite (HDM) extract in vitro. Results provide insight into the molecular mechanisms underlying the allergic response of the nasal epithelia to allergens.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 disease state, 10 individual sets
Platform:
GPL570
Series:
GSE9150
20 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3082
ID:
3082
6.

Genes regulated by inflammatory cytokines in five primary endothelial cell types

(Submitter supplied) Genes regulated by inflammatory cytokines in five primary endothelial cell types Keywords: ordered
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS498 GDS499 GDS501 GDS502
Platform:
GPL371
15 Samples
Download data
Series
Accession:
GSE569
ID:
200000569
7.
Full record GDS502

Inflammatory cytokine effect on primary colon endothelial cells

Examination of gene expression induced by interferon gamma (IFNg), tumor necrosis factor alpha (TNFa) and interleukin 4 (IL4) inflammatory cytokines on primary colon endothelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, log ratio, 3 agent sets
Platform:
GPL371
Series:
GSE569
3 Samples
Download data
DataSet
Accession:
GDS502
ID:
502
8.
Full record GDS501

Inflammatory cytokine effect on primary dermal endothelial cells

Examination of gene expression induced by interferon gamma (IFNg), tumor necrosis factor alpha (TNFa) and interleukin 4 (IL4) inflammatory cytokines on primary dermal endothelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, log ratio, 3 agent sets
Platform:
GPL371
Series:
GSE569
3 Samples
Download data
DataSet
Accession:
GDS501
ID:
501
9.
Full record GDS499

Inflammatory cytokine effect on primary aortic endothelial cells

Examination of gene expression induced by interferon gamma (IFNg), tumor necrosis factor alpha (TNFa) and interleukin 4 (IL4) inflammatory cytokines on primary aortic endothelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, log ratio, 3 agent sets
Platform:
GPL371
Series:
GSE569
3 Samples
Download data
DataSet
Accession:
GDS499
ID:
499
10.
Full record GDS498

Inflammatory cytokine effect on primary lung endothelial cells

Examination of gene expression induced by interferon gamma (IFNg), tumor necrosis factor alpha (TNFa) and interleukin 4 (IL4) inflammatory cytokines on primary lung endothelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, log ratio, 3 agent sets
Platform:
GPL371
Series:
GSE569
3 Samples
Download data
DataSet
Accession:
GDS498
ID:
498
11.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3643
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE10748
ID:
200010748
12.
Full record GDS3643

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 6 dose sets
Platform:
GPL1355
Series:
GSE10748
24 Samples
Download data: CEL
DataSet
Accession:
GDS3643
ID:
3643
13.

HUVEC gene profile after TNF-stimulation

(Submitter supplied) HUVEC were left untreated or stimulated for 5h with 2 ng/ml TNF. Comparsion of the gene profiles revealed TNF-mediated gene expression changes in HUVEC. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1542
Platform:
GPL96
8 Samples
Download data: CEL, EXP
Series
Accession:
GSE2639
ID:
200002639
14.

HMEC gene profile after TNF-stimulation

(Submitter supplied) HMEC cultures were left untreated or stimulated for 5h with 2 ng/ml TNF. Comparison of the gene expression profiles revealed the TNF-mediated gene expression changes. Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1543
Platform:
GPL96
6 Samples
Download data: CEL, EXP
Series
Accession:
GSE2638
ID:
200002638
15.
Full record GDS1543

Tumor necrosis factor effect on microvascular endothelial cells

Analysis of microvascular endothelial cells (HMEC) stimulated with tumor necrosis factor (TNF)-alpha for 5 hours. TNF is a potent inflammatory stimulus. Results provide insight into the relevance of the diversity of endothelial cell subtypes for the response to inflammatory stimuli.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL96
Series:
GSE2638
6 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS1543
ID:
1543
16.
Full record GDS1542

Tumor necrosis factor effect on macrovascular umbilical vein endothelial cells

Analysis of macrovascular umbilical vein endothelial cells (HUVEC) stimulated with tumor necrosis factor (TNF)-alpha for 5 hours. TNF is a potent inflammatory stimulus. Results provide insight into the relevance of the diversity of endothelial cell subtypes for the response to inflammatory stimuli.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL96
Series:
GSE2639
8 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS1542
ID:
1542
17.

airway epithelium, large airways, pre and post-mechanical injury

(Submitter supplied) Responses of the Human Airway Epithelium Transcriptome to In Vivo Injury To identify genes participating in repair of the human airway epithelium following injury, we used bronchoscopy and brushing to denude the airway epithelium of healthy individuals, sequentially sampled the same region 7 and 14 days later, and assessed the recovered epithelium for relative levels of gene expression using Affymetrix high-density oligonucleotide microarrays with TaqMan PCR confirmation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2495
Platform:
GPL570
22 Samples
Download data: CEL
Series
Accession:
GSE5372
ID:
200005372
18.
Full record GDS2495

Airway epithelium response to injury: time course

Analysis of airway epithelia from healthy individuals 7 and 14 days following injury by epithelial denudation. Results provide insight into the molecular mechanisms underlying airway epithelial repair.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 9 individual, 2 other, 2 stress, 3 time sets
Platform:
GPL570
Series:
GSE5372
22 Samples
Download data: CEL
DataSet
Accession:
GDS2495
ID:
2495
19.

interaction with bacteria or bacterial supernatant

(Submitter supplied) Epithelial cells were in contact either with live bacteria (S. aureus) or with bacterial supernatant during 3 hours. Three dependant experiment for each condition were performed. RNA from epithelial cells were extracted. Each condition was hybridized on 6 slides (3 slides with their corresponding swap) Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1521
12 Samples
Download data
Series
Accession:
GSE1853
ID:
200001853
20.

Epithelial cells in contact with bacterial supernatant

(Submitter supplied) Epithelial cells were in contact with bacteria supernatant during different times of incubation. time course supernatant 10 % MM39 Keywords: time-course
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1417
5 Samples
Download data
Series
Accession:
GSE1704
ID:
200001704
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